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Disruption of HIF1Α translational control attenuates the HIF-dependent hypoxic response and solid tumour formation in vivo
Jill E Hunter, Oliver McHugh, Gabrielle B Ecclestone, Fraser Child, Hannah Mearns, Georgia Robson, Molly Dadzie, Sonia Rocha, Neil D Perkins, View ORCID ProfileNiall S Kenneth
doi: https://doi.org/10.1101/2022.11.02.514731
Jill E Hunter
2Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
Oliver McHugh
1Department of Biochemistry and Systems Biology, Institute of Systems, Integrative Biology University of Liverpool, UK
Gabrielle B Ecclestone
1Department of Biochemistry and Systems Biology, Institute of Systems, Integrative Biology University of Liverpool, UK
Fraser Child
1Department of Biochemistry and Systems Biology, Institute of Systems, Integrative Biology University of Liverpool, UK
Hannah Mearns
2Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
Georgia Robson
1Department of Biochemistry and Systems Biology, Institute of Systems, Integrative Biology University of Liverpool, UK
Molly Dadzie
1Department of Biochemistry and Systems Biology, Institute of Systems, Integrative Biology University of Liverpool, UK
Sonia Rocha
1Department of Biochemistry and Systems Biology, Institute of Systems, Integrative Biology University of Liverpool, UK
Neil D Perkins
2Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
Niall S Kenneth
1Department of Biochemistry and Systems Biology, Institute of Systems, Integrative Biology University of Liverpool, UK
2Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
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Posted November 03, 2022.
Disruption of HIF1Α translational control attenuates the HIF-dependent hypoxic response and solid tumour formation in vivo
Jill E Hunter, Oliver McHugh, Gabrielle B Ecclestone, Fraser Child, Hannah Mearns, Georgia Robson, Molly Dadzie, Sonia Rocha, Neil D Perkins, Niall S Kenneth
bioRxiv 2022.11.02.514731; doi: https://doi.org/10.1101/2022.11.02.514731
Disruption of HIF1Α translational control attenuates the HIF-dependent hypoxic response and solid tumour formation in vivo
Jill E Hunter, Oliver McHugh, Gabrielle B Ecclestone, Fraser Child, Hannah Mearns, Georgia Robson, Molly Dadzie, Sonia Rocha, Neil D Perkins, Niall S Kenneth
bioRxiv 2022.11.02.514731; doi: https://doi.org/10.1101/2022.11.02.514731
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