Identification of a unique transcriptomic signature associated with islet amyloidosis

Marko Barovic; Klaus Steinmeyer; Nicole Kipke; Eyke Schöniger; Daniela Friedland; Flavia Marzetta; Almuth Forberger; Gustavo Baretton; Jürgen Weitz; Daniela Aust; Mark Ibberson; Marius Distler; Anke M Schulte; Michele Solimena

doi:10.1101/2022.11.09.515784

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Identification of a unique transcriptomic signature associated with islet amyloidosis

Marko Barovic, Klaus Steinmeyer, Nicole Kipke, Eyke Schöniger, Daniela Friedland, Flavia Marzetta, Almuth Forberger, Gustavo Baretton, Jürgen Weitz, Daniela Aust, Mark Ibberson, Marius Distler, Anke M Schulte, Michele Solimena

doi: https://doi.org/10.1101/2022.11.09.515784

Marko Barovic

1Department of Molecular Diabetology, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany

2Paul Langerhans Institute Dresden (PLID), Helmholtz Center Munich, University Hospital and Faculty of Medicine, TU Dresden, Dresden, Germany

3German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany

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Klaus Steinmeyer

4Sanofi Aventis Deutschland GmbH, Diabetes Research, Industriepark Höchst, Frankfurt am Main, Germany

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Nicole Kipke

1Department of Molecular Diabetology, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany

2Paul Langerhans Institute Dresden (PLID), Helmholtz Center Munich, University Hospital and Faculty of Medicine, TU Dresden, Dresden, Germany

3German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany

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Eyke Schöniger

1Department of Molecular Diabetology, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany

2Paul Langerhans Institute Dresden (PLID), Helmholtz Center Munich, University Hospital and Faculty of Medicine, TU Dresden, Dresden, Germany

3German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany

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Daniela Friedland

1Department of Molecular Diabetology, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany

2Paul Langerhans Institute Dresden (PLID), Helmholtz Center Munich, University Hospital and Faculty of Medicine, TU Dresden, Dresden, Germany

3German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany

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Flavia Marzetta

5Vital-IT Group, SIB Swiss Institute for Bioinformatics, Lausanne, Switzerland

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Almuth Forberger

6Department of Pathology, Medical Faculty, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

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Gustavo Baretton

6Department of Pathology, Medical Faculty, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

7NCT Biobank Dresden, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

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Jürgen Weitz

8Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Dresden, Germany

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Daniela Aust

6Department of Pathology, Medical Faculty, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

7NCT Biobank Dresden, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

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Mark Ibberson

5Vital-IT Group, SIB Swiss Institute for Bioinformatics, Lausanne, Switzerland

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Marius Distler

8Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Dresden, Germany

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Anke M Schulte

4Sanofi Aventis Deutschland GmbH, Diabetes Research, Industriepark Höchst, Frankfurt am Main, Germany

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Michele Solimena

1Department of Molecular Diabetology, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany

2Paul Langerhans Institute Dresden (PLID), Helmholtz Center Munich, University Hospital and Faculty of Medicine, TU Dresden, Dresden, Germany

3German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany

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For correspondence: Michele.Solimena@uniklinikum-dresden.de

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Identification of a unique transcriptomic signature associated with islet amyloidosis

bioRxiv 2022.11.09.515784; doi: https://doi.org/10.1101/2022.11.09.515784

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Identification of a unique transcriptomic signature associated with islet amyloidosis

bioRxiv 2022.11.09.515784; doi: https://doi.org/10.1101/2022.11.09.515784

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