New Results
Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma 3D organoids and identify matrix-activated therapeutic targets
View ORCID ProfileRicardo Cruz-Acuña, Secunda W. Kariuki, Kensuke Sugiura, Claudia Loebel, Tatiana Karakasheva, Joel T. Gabre, Jason A. Burdick, Anil K. Rustgi
doi: https://doi.org/10.1101/2022.11.13.516357
Ricardo Cruz-Acuña
1Herbert Irving Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA
Ph.D.Secunda W. Kariuki
1Herbert Irving Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA
Kensuke Sugiura
1Herbert Irving Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA
M.D., Ph.D.Claudia Loebel
2Department of Materials Science and Engineering, University of Michigan, Ann Arbor, MI, USA
M.D., Ph.D.Tatiana Karakasheva
3Division of Gastroenterology, Hepatology, and Nutrition, Children’s Hospital of Philadelphia, Philadelphia, PA, USA
Ph.D.Joel T. Gabre
1Herbert Irving Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA
M.D.Jason A. Burdick
4BioFrontiers Institute and Department of Chemical and Biological Engineering, University of Colorado, Boulder, CO, USA
Ph.D.Anil K. Rustgi
1Herbert Irving Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA
M.D.
Posted November 16, 2022.
Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma 3D organoids and identify matrix-activated therapeutic targets
Ricardo Cruz-Acuña, Secunda W. Kariuki, Kensuke Sugiura, Claudia Loebel, Tatiana Karakasheva, Joel T. Gabre, Jason A. Burdick, Anil K. Rustgi
bioRxiv 2022.11.13.516357; doi: https://doi.org/10.1101/2022.11.13.516357
Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma 3D organoids and identify matrix-activated therapeutic targets
Ricardo Cruz-Acuña, Secunda W. Kariuki, Kensuke Sugiura, Claudia Loebel, Tatiana Karakasheva, Joel T. Gabre, Jason A. Burdick, Anil K. Rustgi
bioRxiv 2022.11.13.516357; doi: https://doi.org/10.1101/2022.11.13.516357
Subject Area
Subject Areas
- Biochemistry (11739)
- Bioengineering (8750)
- Bioinformatics (29189)
- Biophysics (14967)
- Cancer Biology (12093)
- Cell Biology (17409)
- Clinical Trials (138)
- Developmental Biology (9419)
- Ecology (14178)
- Epidemiology (2067)
- Evolutionary Biology (18301)
- Genetics (12238)
- Genomics (16797)
- Immunology (11865)
- Microbiology (28068)
- Molecular Biology (11583)
- Neuroscience (60953)
- Paleontology (451)
- Pathology (1870)
- Pharmacology and Toxicology (3238)
- Physiology (4957)
- Plant Biology (10425)
- Synthetic Biology (2884)
- Systems Biology (7338)
- Zoology (1651)