Abstract
Transcription factors (TFs) are proteins that directly interpret the genome to regulate gene expression and determine cellular phenotypes. TF identification is a common first step in unravelling gene regulatory networks. We present CREPE, an R Shiny app to catalogue and annotate TFs. CREPE was benchmarked against curated human transcription factor datasets. Next, we use CREPE to explore the TF repertoires of Heliconius erato and Heliconius melpomene butterflies. CREPE is available as a Shiny app package available at GitHub (github.com/dirostri/CREPE).
Competing Interest Statement
The authors have declared no competing interest.
Footnotes
Contact: diego.rosado{at}upr.edu and jose.rodriguez233{at}upr.edu
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
Posted November 16, 2022.
