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Age and Sex-Dependent Differences in Human Cardiac Matrix-Bound Exosomes Modulate Fibrosis through Synergistic miRNA Effects

View ORCID ProfileGeorge Ronan, View ORCID ProfileGokhan Bahcecioglu, Jun Yang, View ORCID ProfilePinar Zorlutuna
doi: https://doi.org/10.1101/2022.11.14.516464
George Ronan
1Bioengineering Graduate Program, University of Notre Dame, Notre Dame, IN, 46556, USA
2Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA
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  • ORCID record for George Ronan
Gokhan Bahcecioglu
2Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA
3Harper Cancer Research Institute, University of Notre Dame, Notre Dame, 46556, USA
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Jun Yang
4Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA
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Pinar Zorlutuna
1Bioengineering Graduate Program, University of Notre Dame, Notre Dame, IN, 46556, USA
2Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA
3Harper Cancer Research Institute, University of Notre Dame, Notre Dame, 46556, USA
4Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA
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  • ORCID record for Pinar Zorlutuna
  • For correspondence: pzorlutu@nd.edu
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Article Information

doi 
https://doi.org/10.1101/2022.11.14.516464
History 
  • November 16, 2022.

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  • You are currently viewing Version 1 of this article (November 16, 2022 - 07:56).
  • View Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. George Ronan1,2,
  2. Gokhan Bahcecioglu2,3,
  3. Jun Yang4 and
  4. Pinar Zorlutuna1,2,3,4,*
  1. 1Bioengineering Graduate Program, University of Notre Dame, Notre Dame, IN, 46556, USA
  2. 2Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA
  3. 3Harper Cancer Research Institute, University of Notre Dame, Notre Dame, 46556, USA
  4. 4Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA
  1. ↵*Corresponding Author: Pinar Zorlutuna; email: pzorlutu{at}nd.edu
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Posted November 16, 2022.
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Age and Sex-Dependent Differences in Human Cardiac Matrix-Bound Exosomes Modulate Fibrosis through Synergistic miRNA Effects
George Ronan, Gokhan Bahcecioglu, Jun Yang, Pinar Zorlutuna
bioRxiv 2022.11.14.516464; doi: https://doi.org/10.1101/2022.11.14.516464
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Age and Sex-Dependent Differences in Human Cardiac Matrix-Bound Exosomes Modulate Fibrosis through Synergistic miRNA Effects
George Ronan, Gokhan Bahcecioglu, Jun Yang, Pinar Zorlutuna
bioRxiv 2022.11.14.516464; doi: https://doi.org/10.1101/2022.11.14.516464

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