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Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks
Baolei Yuan, Chongwei Bi, Jinchen Wang, Yiqing Jin, Khaled Alsayegh, Muhammad Tehseen, Gang Yi, Samir Hamdan, View ORCID ProfileYanyi Huang, View ORCID ProfileMo Li
doi: https://doi.org/10.1101/2022.11.16.516713
Baolei Yuan
1Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia
Chongwei Bi
1Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia
Jinchen Wang
2Beijing Advanced Innovation Center for Genomics (ICG), Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, College of Chemistry, College of Engineering, Peking-Tsinghua Center for Life sciences, Peking University, Beijing, China
Yiqing Jin
1Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia
Khaled Alsayegh
1Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia
Muhammad Tehseen
1Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia
Gang Yi
1Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia
Samir Hamdan
1Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia
Yanyi Huang
2Beijing Advanced Innovation Center for Genomics (ICG), Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, College of Chemistry, College of Engineering, Peking-Tsinghua Center for Life sciences, Peking University, Beijing, China
3Institute for Cell Analysis, Shenzhen Bay laboratory, Shenzhen, China
Mo Li
1Bioscience Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia
4Bioengineering Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia

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Posted November 16, 2022.
Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks
Baolei Yuan, Chongwei Bi, Jinchen Wang, Yiqing Jin, Khaled Alsayegh, Muhammad Tehseen, Gang Yi, Samir Hamdan, Yanyi Huang, Mo Li
bioRxiv 2022.11.16.516713; doi: https://doi.org/10.1101/2022.11.16.516713
Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks
Baolei Yuan, Chongwei Bi, Jinchen Wang, Yiqing Jin, Khaled Alsayegh, Muhammad Tehseen, Gang Yi, Samir Hamdan, Yanyi Huang, Mo Li
bioRxiv 2022.11.16.516713; doi: https://doi.org/10.1101/2022.11.16.516713
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