Integrative single cell multiomics analysis of human retina indicates a role for hierarchical transcription factors collaboration in genetic effects on gene regulation

Jun Wang; Xuesen Cheng; Qingnan Liang; Leah A. Owen; Meng Wang; Margaret M. DeAngelis; Yumei Li; Rui Chen

doi:10.1101/2022.11.16.516814

New Results

Integrative single cell multiomics analysis of human retina indicates a role for hierarchical transcription factors collaboration in genetic effects on gene regulation

Jun Wang, Xuesen Cheng, Qingnan Liang, Leah A. Owen, Meng Wang, Margaret M. DeAngelis, Yumei Li, Rui Chen

doi: https://doi.org/10.1101/2022.11.16.516814

Jun Wang

1Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA

2Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Xuesen Cheng

1Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA

2Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Qingnan Liang

1Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA

2Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA

3Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Leah A. Owen

4John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Meng Wang

1Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA

2Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Margaret M. DeAngelis

5Department of Ophthalmology, University at Buffalo the State University of New York, Buffalo, NY, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yumei Li

1Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA

2Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Rui Chen

1Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA

2Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: ruichen@bcm.edu

Abstract
Full Text
Info/History
Metrics
Supplementary material
Preview PDF

Supplementary Information[supplements/516814_file10.pdf]
Supplementary Tables 1-7[supplements/516814_file11.xlsx]

View the discussion thread.

PreviousNext

Posted November 17, 2022.

Download PDF

Supplementary Material

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Integrative single cell multiomics analysis of human retina indicates a role for hierarchical transcription factors collaboration in genetic effects on gene regulation

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Integrative single cell multiomics analysis of human retina indicates a role for hierarchical transcription factors collaboration in genetic effects on gene regulation

Jun Wang, Xuesen Cheng, Qingnan Liang, Leah A. Owen, Meng Wang, Margaret M. DeAngelis, Yumei Li, Rui Chen

bioRxiv 2022.11.16.516814; doi: https://doi.org/10.1101/2022.11.16.516814

Share This Article:

Citation Tools

Integrative single cell multiomics analysis of human retina indicates a role for hierarchical transcription factors collaboration in genetic effects on gene regulation

Jun Wang, Xuesen Cheng, Qingnan Liang, Leah A. Owen, Meng Wang, Margaret M. DeAngelis, Yumei Li, Rui Chen

bioRxiv 2022.11.16.516814; doi: https://doi.org/10.1101/2022.11.16.516814

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Genomics

Subject Areas

All Articles

Animal Behavior and Cognition (5713)
Biochemistry (12953)
Bioengineering (9844)
Bioinformatics (31575)
Biophysics (16279)
Cancer Biology (13355)
Cell Biology (19036)
Clinical Trials (138)
Developmental Biology (10317)
Ecology (15329)
Epidemiology (2067)
Evolutionary Biology (19573)
Genetics (12984)
Genomics (17950)
Immunology (13067)
Microbiology (30538)
Molecular Biology (12729)
Neuroscience (66644)
Paleontology (490)
Pathology (2063)
Pharmacology and Toxicology (3550)
Physiology (5537)
Plant Biology (11412)
Scientific Communication and Education (1751)
Synthetic Biology (3174)
Systems Biology (7838)
Zoology (1769)