Formamide significantly enhances the efficiency of chemical adenylation of RNA sequencing ligation adaptors

Samuel R. Hildebrand; Adam K. Hedger; Jonathan K. Watts; Anastasia Khvorova

doi:10.1101/2022.11.16.516815

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Formamide significantly enhances the efficiency of chemical adenylation of RNA sequencing ligation adaptors

View ORCID ProfileSamuel R. Hildebrand, View ORCID ProfileAdam K. Hedger, View ORCID ProfileJonathan K. Watts, View ORCID ProfileAnastasia Khvorova

doi: https://doi.org/10.1101/2022.11.16.516815

Samuel R. Hildebrand

1RNA Therapeutics Institute, University of Massachusetts Chan Medical School; Worcester, USA

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Adam K. Hedger

1RNA Therapeutics Institute, University of Massachusetts Chan Medical School; Worcester, USA

2Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School; Worcester, USA

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Jonathan K. Watts

1RNA Therapeutics Institute, University of Massachusetts Chan Medical School; Worcester, USA

2Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School; Worcester, USA

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ORCID record for Jonathan K. Watts

Anastasia Khvorova

1RNA Therapeutics Institute, University of Massachusetts Chan Medical School; Worcester, USA

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ORCID record for Anastasia Khvorova
For correspondence: anastasia.khvorova@umassmed.edu

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Formamide significantly enhances the efficiency of chemical adenylation of RNA sequencing ligation adaptors

Samuel R. Hildebrand, Adam K. Hedger, Jonathan K. Watts, Anastasia Khvorova

bioRxiv 2022.11.16.516815; doi: https://doi.org/10.1101/2022.11.16.516815

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Formamide significantly enhances the efficiency of chemical adenylation of RNA sequencing ligation adaptors

Samuel R. Hildebrand, Adam K. Hedger, Jonathan K. Watts, Anastasia Khvorova

bioRxiv 2022.11.16.516815; doi: https://doi.org/10.1101/2022.11.16.516815

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