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Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits

Daisy J. Grove, Daniel J. Levine, Michael G. Kearse
doi: https://doi.org/10.1101/2022.11.18.517125
Daisy J. Grove
1The Ohio State Biochemistry Program, The Ohio State University, Columbus, OH 43210 USA
2Department of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH 43210 USA
3Center for RNA Biology, The Ohio State University, Columbus, OH 43210 USA
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Daniel J. Levine
2Department of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH 43210 USA
3Center for RNA Biology, The Ohio State University, Columbus, OH 43210 USA
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Michael G. Kearse
1The Ohio State Biochemistry Program, The Ohio State University, Columbus, OH 43210 USA
2Department of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH 43210 USA
3Center for RNA Biology, The Ohio State University, Columbus, OH 43210 USA
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  • For correspondence: michael.kearse@osumc.edu
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Article Information

doi 
https://doi.org/10.1101/2022.11.18.517125
History 
  • November 21, 2022.

Article Versions

  • Version 1 (November 18, 2022 - 17:14).
  • You are viewing Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Daisy J. Grove1,2,3,
  2. Daniel J. Levine2,3 and
  3. Michael G. Kearse1,2,3,*
  1. 1The Ohio State Biochemistry Program, The Ohio State University, Columbus, OH 43210 USA
  2. 2Department of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH 43210 USA
  3. 3Center for RNA Biology, The Ohio State University, Columbus, OH 43210 USA
  1. ↵*Correspondence: michael.kearse{at}osumc.edu
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Posted November 21, 2022.
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Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits
Daisy J. Grove, Daniel J. Levine, Michael G. Kearse
bioRxiv 2022.11.18.517125; doi: https://doi.org/10.1101/2022.11.18.517125
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Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits
Daisy J. Grove, Daniel J. Levine, Michael G. Kearse
bioRxiv 2022.11.18.517125; doi: https://doi.org/10.1101/2022.11.18.517125

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