New Results
Starfysh reveals heterogeneous spatial dynamics in the breast tumor microenvironment
Siyu He, Yinuo Jin, Achille Nazaret, Lingting Shi, Xueer Chen, Sham Rampersaud, Bahawar S. Dhillon, Izabella Valdez, Lauren E Friend, Joy Linyue Fan, Cameron Y Park, Rachel Mintz, Yeh-Hsing Lao, David Carrera, Kaylee W Fang, Kaleem Mehdi, Madeline Rohde, José L. McFaline-Figueroa, David Blei, Kam W. Leong, Alexander Y Rudensky, George Plitas, Elham Azizi
doi: https://doi.org/10.1101/2022.11.21.517420
Siyu He
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
2Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA
Yinuo Jin
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
2Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA
Achille Nazaret
2Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA
3Department of Computer Science, Columbia University, New York, NY 10027, USA
Lingting Shi
2Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA
Xueer Chen
2Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA
Sham Rampersaud
4Pharmaceutical Sciences and Pharmacogenomics Graduate Program, University of California, San Francisco, CA 94143, USA
Bahawar S. Dhillon
5Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Izabella Valdez
6Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Lauren E Friend
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
2Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA
Joy Linyue Fan
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
2Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA
Cameron Y Park
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
2Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA
Rachel Mintz
7Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130
Yeh-Hsing Lao
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
8Department of Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo NY 14214
David Carrera
3Department of Computer Science, Columbia University, New York, NY 10027, USA
Kaylee W Fang
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
3Department of Computer Science, Columbia University, New York, NY 10027, USA
Kaleem Mehdi
9Department of Biological Sciences, Fordham University, New York, NY 10458, USA
Madeline Rohde
10Briarcliff High School, Briarcliff Manor, New York, NY 10510, USA
José L. McFaline-Figueroa
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
2Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA
11Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA
David Blei
3Department of Computer Science, Columbia University, New York, NY 10027, USA
12Department of Statistics, Columbia University, New York, NY, USA
Kam W. Leong
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
11Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA
13Department of Systems Biology, Columbia University Irving Medical Center, New York 10027, NY 10032, USA
Alexander Y Rudensky
5Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
14Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York 10027, NY 10065, USA
15Ludwig Center at Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
George Plitas
5Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
14Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York 10027, NY 10065, USA
15Ludwig Center at Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
16Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Elham Azizi
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
2Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA
3Department of Computer Science, Columbia University, New York, NY 10027, USA
11Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA
17Data Science Institute, Columbia University, New York, NY 10027, USA
Posted November 24, 2022.
Starfysh reveals heterogeneous spatial dynamics in the breast tumor microenvironment
Siyu He, Yinuo Jin, Achille Nazaret, Lingting Shi, Xueer Chen, Sham Rampersaud, Bahawar S. Dhillon, Izabella Valdez, Lauren E Friend, Joy Linyue Fan, Cameron Y Park, Rachel Mintz, Yeh-Hsing Lao, David Carrera, Kaylee W Fang, Kaleem Mehdi, Madeline Rohde, José L. McFaline-Figueroa, David Blei, Kam W. Leong, Alexander Y Rudensky, George Plitas, Elham Azizi
bioRxiv 2022.11.21.517420; doi: https://doi.org/10.1101/2022.11.21.517420
Starfysh reveals heterogeneous spatial dynamics in the breast tumor microenvironment
Siyu He, Yinuo Jin, Achille Nazaret, Lingting Shi, Xueer Chen, Sham Rampersaud, Bahawar S. Dhillon, Izabella Valdez, Lauren E Friend, Joy Linyue Fan, Cameron Y Park, Rachel Mintz, Yeh-Hsing Lao, David Carrera, Kaylee W Fang, Kaleem Mehdi, Madeline Rohde, José L. McFaline-Figueroa, David Blei, Kam W. Leong, Alexander Y Rudensky, George Plitas, Elham Azizi
bioRxiv 2022.11.21.517420; doi: https://doi.org/10.1101/2022.11.21.517420
Subject Area
Subject Areas
- Biochemistry (11699)
- Bioengineering (8715)
- Bioinformatics (29119)
- Biophysics (14927)
- Cancer Biology (12047)
- Cell Biology (17347)
- Clinical Trials (138)
- Developmental Biology (9405)
- Ecology (14138)
- Epidemiology (2067)
- Evolutionary Biology (18261)
- Genetics (12216)
- Genomics (16760)
- Immunology (11839)
- Microbiology (27996)
- Molecular Biology (11549)
- Neuroscience (60781)
- Paleontology (450)
- Pathology (1864)
- Pharmacology and Toxicology (3228)
- Physiology (4937)
- Plant Biology (10382)
- Synthetic Biology (2876)
- Systems Biology (7332)
- Zoology (1642)