Lidocaine Induces Apoptosis in Head and Neck Squamous Cell Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14

Zoey A. Miller; Jennifer F. Jolivert; Ray Z. Ma; Sahil Muthuswami; Arielle Mueller; Derek B. McMahon; Ryan M. Carey; Robert J. Lee

doi:10.1101/2022.11.22.517413

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Lidocaine Induces Apoptosis in Head and Neck Squamous Cell Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14

View ORCID ProfileZoey A. Miller, Jennifer F. Jolivert, Ray Z. Ma, Sahil Muthuswami, Arielle Mueller, Derek B. McMahon, View ORCID ProfileRyan M. Carey, View ORCID ProfileRobert J. Lee

doi: https://doi.org/10.1101/2022.11.22.517413

Zoey A. Miller

1Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

2Pharmacology Graduate Group

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ORCID record for Zoey A. Miller

Jennifer F. Jolivert

1Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

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Ray Z. Ma

3Harriton High School, Bryn Mawr, PA

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Sahil Muthuswami

1Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

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Arielle Mueller

1Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

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Derek B. McMahon

1Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

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Ryan M. Carey

1Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

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Robert J. Lee

1Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

4Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

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For correspondence: rjl@pennmedicine.upenn.edu

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Lidocaine Induces Apoptosis in Head and Neck Squamous Cell Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14

Zoey A. Miller, Jennifer F. Jolivert, Ray Z. Ma, Sahil Muthuswami, Arielle Mueller, Derek B. McMahon, Ryan M. Carey, Robert J. Lee

bioRxiv 2022.11.22.517413; doi: https://doi.org/10.1101/2022.11.22.517413

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Lidocaine Induces Apoptosis in Head and Neck Squamous Cell Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14

Zoey A. Miller, Jennifer F. Jolivert, Ray Z. Ma, Sahil Muthuswami, Arielle Mueller, Derek B. McMahon, Ryan M. Carey, Robert J. Lee

bioRxiv 2022.11.22.517413; doi: https://doi.org/10.1101/2022.11.22.517413

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