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Deficits in integrative NMDA receptors caused by Grin1 disruption can be rescued in adulthood

View ORCID ProfileS. Venkatesan, M.A. Binko, View ORCID ProfileC.A. Mielnik, View ORCID ProfileA.J. Ramsey, View ORCID ProfileE.K. Lambe
doi: https://doi.org/10.1101/2022.11.22.517556
S. Venkatesan
1Department of Physiology, University of Toronto, ON, Canada
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M.A. Binko
1Department of Physiology, University of Toronto, ON, Canada
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C.A. Mielnik
2Department of Pharmacology and Toxicology, University of Toronto, ON, Canada
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A.J. Ramsey
1Department of Physiology, University of Toronto, ON, Canada
2Department of Pharmacology and Toxicology, University of Toronto, ON, Canada
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E.K. Lambe
1Department of Physiology, University of Toronto, ON, Canada
3Department of OBGYN, University of Toronto, ON, Canada
4Department of Psychiatry, University of Toronto, ON, Canada
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  • For correspondence: evelyn.lambe@utoronto.ca
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Article Information

doi 
https://doi.org/10.1101/2022.11.22.517556
History 
  • November 23, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.

Author Information

  1. S. Venkatesan1,*,
  2. M.A. Binko1,*,#,
  3. C.A. Mielnik2,
  4. A.J. Ramsey1,2 and
  5. E.K. Lambe1,3,4,†
  1. 1Department of Physiology, University of Toronto, ON, Canada
  2. 2Department of Pharmacology and Toxicology, University of Toronto, ON, Canada
  3. 3Department of OBGYN, University of Toronto, ON, Canada
  4. 4Department of Psychiatry, University of Toronto, ON, Canada
  1. ↵†Corresponding author: E. K. Lambe, Ph.D. Department of Physiology, Temerty Faculty of Medicine, University of Toronto, 1 King’s College Circle, Toronto ON M5S 1A8, Phone: 416-946-0910, Email: evelyn.lambe{at}utoronto.ca
  1. ↵* Equally-contributing co-first authors

  2. Author contributions: designed study (MAB, SV, EKL), conducted experiments and analyzed data (MAB, SV), contributed tools (AJR), wrote first draft of paper (MAB, SV), wrote and revised paper (MAB, SV, CAM, AJR, EKL).

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Posted November 23, 2022.
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Deficits in integrative NMDA receptors caused by Grin1 disruption can be rescued in adulthood
S. Venkatesan, M.A. Binko, C.A. Mielnik, A.J. Ramsey, E.K. Lambe
bioRxiv 2022.11.22.517556; doi: https://doi.org/10.1101/2022.11.22.517556
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Deficits in integrative NMDA receptors caused by Grin1 disruption can be rescued in adulthood
S. Venkatesan, M.A. Binko, C.A. Mielnik, A.J. Ramsey, E.K. Lambe
bioRxiv 2022.11.22.517556; doi: https://doi.org/10.1101/2022.11.22.517556

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