A preclinical model of THC edibles that produces high-dose cannabimimetic responses

Anthony English; Fleur Uittenbogaard; Alexa Torrens; Dennis Sarroza; Anna Slaven; Danielle Piomelli; Michael Bruchas; Nephi Stella; Benjamin Land

doi:10.1101/2022.11.23.517743

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A preclinical model of THC edibles that produces high-dose cannabimimetic responses

Anthony English, Fleur Uittenbogaard, Alexa Torrens, Dennis Sarroza, Anna Slaven, Danielle Piomelli, Michael Bruchas, Nephi Stella, Benjamin Land

doi: https://doi.org/10.1101/2022.11.23.517743

Anthony English

1Departments of Pharmacology, University of Washington, Seattle WA 98195

2UW Center of Excellence in Neurobiology of Addiction, Pain, and Emotion (NAPE), University of Washington, Seattle WA 98195

3Center for Cannabis Research, University of Washington, Seattle WA 98195

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Fleur Uittenbogaard

1Departments of Pharmacology, University of Washington, Seattle WA 98195

2UW Center of Excellence in Neurobiology of Addiction, Pain, and Emotion (NAPE), University of Washington, Seattle WA 98195

3Center for Cannabis Research, University of Washington, Seattle WA 98195

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Alexa Torrens

4Department of Anatomy & Neurobiology, University of California Irvine, Irvine CA

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Dennis Sarroza

1Departments of Pharmacology, University of Washington, Seattle WA 98195

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Anna Slaven

1Departments of Pharmacology, University of Washington, Seattle WA 98195

2UW Center of Excellence in Neurobiology of Addiction, Pain, and Emotion (NAPE), University of Washington, Seattle WA 98195

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Danielle Piomelli

4Department of Anatomy & Neurobiology, University of California Irvine, Irvine CA

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Michael Bruchas

1Departments of Pharmacology, University of Washington, Seattle WA 98195

2UW Center of Excellence in Neurobiology of Addiction, Pain, and Emotion (NAPE), University of Washington, Seattle WA 98195

3Center for Cannabis Research, University of Washington, Seattle WA 98195

4Department of Anatomy & Neurobiology, University of California Irvine, Irvine CA

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Nephi Stella

1Departments of Pharmacology, University of Washington, Seattle WA 98195

2UW Center of Excellence in Neurobiology of Addiction, Pain, and Emotion (NAPE), University of Washington, Seattle WA 98195

3Center for Cannabis Research, University of Washington, Seattle WA 98195

6Psychiatry & Behavioral Sciences, University of Washington, Seattle WA 98195

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For correspondence: nsetlla@uw.edu

Benjamin Land

1Departments of Pharmacology, University of Washington, Seattle WA 98195

2UW Center of Excellence in Neurobiology of Addiction, Pain, and Emotion (NAPE), University of Washington, Seattle WA 98195

3Center for Cannabis Research, University of Washington, Seattle WA 98195

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A preclinical model of THC edibles that produces high-dose cannabimimetic responses

Anthony English, Fleur Uittenbogaard, Alexa Torrens, Dennis Sarroza, Anna Slaven, Danielle Piomelli, Michael Bruchas, Nephi Stella, Benjamin Land

bioRxiv 2022.11.23.517743; doi: https://doi.org/10.1101/2022.11.23.517743

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A preclinical model of THC edibles that produces high-dose cannabimimetic responses

Anthony English, Fleur Uittenbogaard, Alexa Torrens, Dennis Sarroza, Anna Slaven, Danielle Piomelli, Michael Bruchas, Nephi Stella, Benjamin Land

bioRxiv 2022.11.23.517743; doi: https://doi.org/10.1101/2022.11.23.517743

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