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Lactate-derived HDAC6 Lactylation as a new target for neuronal protection in cerebral ischemic reperfusion injury

View ORCID ProfileJun Cao, View ORCID ProfileZexuan Hong, View ORCID ProfileFanning Zeng, View ORCID ProfileZaisheng Qin, View ORCID ProfileMiao Lin, View ORCID ProfileHao Wang, View ORCID ProfileDaming Zuo, View ORCID ProfileTao Tao
doi: https://doi.org/10.1101/2022.11.27.518054
Jun Cao
1Department of Anesthesiology, Affiliated Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, Guangdong 518000, China
2Department of Anesthesiology, Central People’s Hospital of Zhanjiang, Zhanjiang, Guangdong 524045, China
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Zexuan Hong
1Department of Anesthesiology, Affiliated Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, Guangdong 518000, China
2Department of Anesthesiology, Central People’s Hospital of Zhanjiang, Zhanjiang, Guangdong 524045, China
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Fanning Zeng
3Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China
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Zaisheng Qin
3Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China
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Miao Lin
4Department of Anesthesiology, First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China
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Hao Wang
4Department of Anesthesiology, First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China
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Daming Zuo
5Department of Medical Laboratory, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, Guangdong 510515, China
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  • For correspondence: taotaomzk@smu.edu.cn zdaming@smu.edu.cn
Tao Tao
2Department of Anesthesiology, Central People’s Hospital of Zhanjiang, Zhanjiang, Guangdong 524045, China
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  • ORCID record for Tao Tao
  • For correspondence: taotaomzk@smu.edu.cn zdaming@smu.edu.cn
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Posted November 27, 2022.
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Lactate-derived HDAC6 Lactylation as a new target for neuronal protection in cerebral ischemic reperfusion injury
Jun Cao, Zexuan Hong, Fanning Zeng, Zaisheng Qin, Miao Lin, Hao Wang, Daming Zuo, Tao Tao
bioRxiv 2022.11.27.518054; doi: https://doi.org/10.1101/2022.11.27.518054
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Lactate-derived HDAC6 Lactylation as a new target for neuronal protection in cerebral ischemic reperfusion injury
Jun Cao, Zexuan Hong, Fanning Zeng, Zaisheng Qin, Miao Lin, Hao Wang, Daming Zuo, Tao Tao
bioRxiv 2022.11.27.518054; doi: https://doi.org/10.1101/2022.11.27.518054

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