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The RNA binding proteins hnRNP H and F regulate splicing of a MYC dependent HRAS exon in Prostate Cancer Cells

Xinyuan Chen, Harry Taegyun Yang, Beatrice Zhang, John W. Phillips, Donghui Cheng, Frank Rigo, Owen N. Witte, Yi Xing, Douglas L. Black
doi: https://doi.org/10.1101/2022.11.29.518269
Xinyuan Chen
1Molecular Biology Interdepartmental Doctoral Program, University of California, Los Angeles, Los Angeles, California 90095, USA
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Harry Taegyun Yang
2Bioinformatics Interdepartmental Graduate Program, University of California, Los Angeles, California 90095, USA
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Beatrice Zhang
3Center for Computational and Genomic Medicine, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
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John W. Phillips
4Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California 90095, USA
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Donghui Cheng
4Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California 90095, USA
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Frank Rigo
5Ionis Pharmaceuticals, Inc., 2855 Gazelle Ct., Carlsbad, California 92010, USA
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Owen N. Witte
4Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California 90095, USA
6Department of Molecular and Medical Pharmacology, University of California, Los Angeles, California 90095, USA
7Jonsson Comprehensive Cancer Center, University of California, Los Angeles, California 90095, USA
8Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, California 90095, USA.
9Molecular Biology Institute, University of California, Los Angeles, California 90095, USA
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Yi Xing
3Center for Computational and Genomic Medicine, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
10Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
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  • For correspondence: dougb@microbio.ucla.edu xingyi@chop.edu
Douglas L. Black
4Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California 90095, USA
7Jonsson Comprehensive Cancer Center, University of California, Los Angeles, California 90095, USA
8Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, California 90095, USA.
9Molecular Biology Institute, University of California, Los Angeles, California 90095, USA
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  • For correspondence: dougb@microbio.ucla.edu xingyi@chop.edu
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The RNA binding proteins hnRNP H and F regulate splicing of a MYC dependent HRAS exon in Prostate Cancer Cells
Xinyuan Chen, Harry Taegyun Yang, Beatrice Zhang, John W. Phillips, Donghui Cheng, Frank Rigo, Owen N. Witte, Yi Xing, Douglas L. Black
bioRxiv 2022.11.29.518269; doi: https://doi.org/10.1101/2022.11.29.518269
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The RNA binding proteins hnRNP H and F regulate splicing of a MYC dependent HRAS exon in Prostate Cancer Cells
Xinyuan Chen, Harry Taegyun Yang, Beatrice Zhang, John W. Phillips, Donghui Cheng, Frank Rigo, Owen N. Witte, Yi Xing, Douglas L. Black
bioRxiv 2022.11.29.518269; doi: https://doi.org/10.1101/2022.11.29.518269

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