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Single-Cell Epitope-Transcriptomics Reveal Lung Stromal and Immune Cell Response Kinetics to Nanoparticle-delivered RIG-I and TLR4 Agonists

M. Cole Keenum, View ORCID ProfileParamita Chatterjee, View ORCID ProfileAlexandra Atalis, View ORCID ProfileBhawana Pandey, View ORCID ProfileAngela Jimenez, View ORCID ProfileKrishnendu Roy
doi: https://doi.org/10.1101/2022.11.29.518316
M. Cole Keenum
1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA
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Paramita Chatterjee
2Marcus Center for Therapeutic Cell Characterization and Manufacturing, Georgia Institute of Technology, Atlanta, Georgia, USA
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  • ORCID record for Paramita Chatterjee
Alexandra Atalis
1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA
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  • ORCID record for Alexandra Atalis
Bhawana Pandey
1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA
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  • ORCID record for Bhawana Pandey
Angela Jimenez
1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA
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  • ORCID record for Angela Jimenez
Krishnendu Roy
1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA
2Marcus Center for Therapeutic Cell Characterization and Manufacturing, Georgia Institute of Technology, Atlanta, Georgia, USA
3The Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, Georgia, USA
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  • ORCID record for Krishnendu Roy
  • For correspondence: krish.roy@gatech.edu
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Article Information

doi 
https://doi.org/10.1101/2022.11.29.518316
History 
  • November 29, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. M. Cole Keenum1,
  2. Paramita Chatterjee2,
  3. Alexandra Atalis1,
  4. Bhawana Pandey1,
  5. Angela Jimenez1 and
  6. Krishnendu Roy*,1,2,3
  1. 1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA
  2. 2Marcus Center for Therapeutic Cell Characterization and Manufacturing, Georgia Institute of Technology, Atlanta, Georgia, USA
  3. 3The Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, Georgia, USA
  1. ↵*Corresponding author email: krish.roy{at}gatech.edu, Corresponding author mailing address: Krone Engineered Biosystems Building, 950 Atlantic Drive NW, Atlanta, Georgia, 30332
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Single-Cell Epitope-Transcriptomics Reveal Lung Stromal and Immune Cell Response Kinetics to Nanoparticle-delivered RIG-I and TLR4 Agonists
M. Cole Keenum, Paramita Chatterjee, Alexandra Atalis, Bhawana Pandey, Angela Jimenez, Krishnendu Roy
bioRxiv 2022.11.29.518316; doi: https://doi.org/10.1101/2022.11.29.518316
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Single-Cell Epitope-Transcriptomics Reveal Lung Stromal and Immune Cell Response Kinetics to Nanoparticle-delivered RIG-I and TLR4 Agonists
M. Cole Keenum, Paramita Chatterjee, Alexandra Atalis, Bhawana Pandey, Angela Jimenez, Krishnendu Roy
bioRxiv 2022.11.29.518316; doi: https://doi.org/10.1101/2022.11.29.518316

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