Coupled mechanical mapping and interference contrast microscopy reveal viscoelastic and adhesion hallmarks of monocytes differentiation into macrophages

Mar Eroles; Javier Lopez-Alonso; Alexandre Ortega; Thomas Boudier; Khaldoun Gharzeddine; Frank Lafont; Clemens M. Franz; Arnaud Millet; Claire Valoteau; Felix Rico

doi:10.1101/2022.11.29.518356

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Coupled mechanical mapping and interference contrast microscopy reveal viscoelastic and adhesion hallmarks of monocytes differentiation into macrophages

View ORCID ProfileMar Eroles, Javier Lopez-Alonso, Alexandre Ortega, Thomas Boudier, Khaldoun Gharzeddine, Frank Lafont, Clemens M. Franz, Arnaud Millet, Claire Valoteau, Felix Rico

doi: https://doi.org/10.1101/2022.11.29.518356

Mar Eroles

1Aix-Marseille University, INSERM, CNRS, LAI (U1067), Turing Centre for Living Systems, Marseille, France

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ORCID record for Mar Eroles

Javier Lopez-Alonso

2Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, F-59000 Lille, France

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Alexandre Ortega

1Aix-Marseille University, INSERM, CNRS, LAI (U1067), Turing Centre for Living Systems, Marseille, France

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Thomas Boudier

3Centuri, Turing Centre for Living Systems, Marseille, France

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Khaldoun Gharzeddine

4Univ.Grenoble Alpes, Inserm U1209, CNRS UMR5309, Institute for Advanced Biosciences, Team Mechanobiology, Immunity and Cancer, 38700 La Tronche, France

5Department of Hepatogastroenterology, Centre Hospitalier Universitaire de Grenoble Alpes, 38700 La Tronche, France

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Frank Lafont

2Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, F-59000 Lille, France

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Clemens M. Franz

6WPI Nano Life Science Institute, Kanazawa University, Kanazawa, Japan

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Arnaud Millet

4Univ.Grenoble Alpes, Inserm U1209, CNRS UMR5309, Institute for Advanced Biosciences, Team Mechanobiology, Immunity and Cancer, 38700 La Tronche, France

5Department of Hepatogastroenterology, Centre Hospitalier Universitaire de Grenoble Alpes, 38700 La Tronche, France

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Claire Valoteau

1Aix-Marseille University, INSERM, CNRS, LAI (U1067), Turing Centre for Living Systems, Marseille, France

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Felix Rico

1Aix-Marseille University, INSERM, CNRS, LAI (U1067), Turing Centre for Living Systems, Marseille, France

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For correspondence: felix.rico@inserm.fr

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Coupled mechanical mapping and interference contrast microscopy reveal viscoelastic and adhesion hallmarks of monocytes differentiation into macrophages

Mar Eroles, Javier Lopez-Alonso, Alexandre Ortega, Thomas Boudier, Khaldoun Gharzeddine, Frank Lafont, Clemens M. Franz, Arnaud Millet, Claire Valoteau, Felix Rico

bioRxiv 2022.11.29.518356; doi: https://doi.org/10.1101/2022.11.29.518356

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Coupled mechanical mapping and interference contrast microscopy reveal viscoelastic and adhesion hallmarks of monocytes differentiation into macrophages

Mar Eroles, Javier Lopez-Alonso, Alexandre Ortega, Thomas Boudier, Khaldoun Gharzeddine, Frank Lafont, Clemens M. Franz, Arnaud Millet, Claire Valoteau, Felix Rico

bioRxiv 2022.11.29.518356; doi: https://doi.org/10.1101/2022.11.29.518356

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