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Temporal landscape of mitochondrial proteostasis governed by the UPRmt

View ORCID ProfileLouise Uoselis, View ORCID ProfileRuna Lindblom, View ORCID ProfileMarvin Skulsuppaisarn, Grace Khuu, View ORCID ProfileThanh N. Nguyen, View ORCID ProfileDanielle L. Rudler, View ORCID ProfileAleksandra Filipovska, View ORCID ProfileRalf B. Schittenhelm, View ORCID ProfileMichael Lazarou
doi: https://doi.org/10.1101/2022.11.30.518286
Louise Uoselis
1Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Australia
2Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
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  • ORCID record for Louise Uoselis
Runa Lindblom
2Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
6Aligning Science Across Parkinson’s Collaborative Research Network, Chevy Chase, MD 20185, USA
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Marvin Skulsuppaisarn
1Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Australia
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  • ORCID record for Marvin Skulsuppaisarn
Grace Khuu
2Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
6Aligning Science Across Parkinson’s Collaborative Research Network, Chevy Chase, MD 20185, USA
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Thanh N. Nguyen
2Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
6Aligning Science Across Parkinson’s Collaborative Research Network, Chevy Chase, MD 20185, USA
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  • ORCID record for Thanh N. Nguyen
Danielle L. Rudler
3Harry Perkins Institute of Medical Research and ARC Centre of Excellence in Synthetic Biology, Nedlands, Western Australia, Australia
4Telethon Kids Institute, Northern Entrance, Perth Children’s Hospital, Nedlands, Western Australia, Australia
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Aleksandra Filipovska
3Harry Perkins Institute of Medical Research and ARC Centre of Excellence in Synthetic Biology, Nedlands, Western Australia, Australia
4Telethon Kids Institute, Northern Entrance, Perth Children’s Hospital, Nedlands, Western Australia, Australia
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  • ORCID record for Aleksandra Filipovska
Ralf B. Schittenhelm
5Monash Proteomics and Metabolomics Facility, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Australia.
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Michael Lazarou
1Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Australia
2Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
6Aligning Science Across Parkinson’s Collaborative Research Network, Chevy Chase, MD 20185, USA
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  • For correspondence: lazarou.m@wehi.edu.au
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Article Information

doi 
https://doi.org/10.1101/2022.11.30.518286
History 
  • November 30, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Louise Uoselis1,2,
  2. Runa Lindblom2,6,
  3. Marvin Skulsuppaisarn1,
  4. Grace Khuu2,6,
  5. Thanh N. Nguyen2,6,
  6. Danielle L. Rudler3,4,
  7. Aleksandra Filipovska3,4,
  8. Ralf B. Schittenhelm5 and
  9. Michael Lazarou1,2,6,*
  1. 1Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Australia
  2. 2Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
  3. 3Harry Perkins Institute of Medical Research and ARC Centre of Excellence in Synthetic Biology, Nedlands, Western Australia, Australia
  4. 4Telethon Kids Institute, Northern Entrance, Perth Children’s Hospital, Nedlands, Western Australia, Australia
  5. 5Monash Proteomics and Metabolomics Facility, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Australia.
  6. 6Aligning Science Across Parkinson’s Collaborative Research Network, Chevy Chase, MD 20185, USA
  1. ↵*Correspondence: lazarou.m{at}wehi.edu.au
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Posted November 30, 2022.
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Temporal landscape of mitochondrial proteostasis governed by the UPRmt
Louise Uoselis, Runa Lindblom, Marvin Skulsuppaisarn, Grace Khuu, Thanh N. Nguyen, Danielle L. Rudler, Aleksandra Filipovska, Ralf B. Schittenhelm, Michael Lazarou
bioRxiv 2022.11.30.518286; doi: https://doi.org/10.1101/2022.11.30.518286
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Temporal landscape of mitochondrial proteostasis governed by the UPRmt
Louise Uoselis, Runa Lindblom, Marvin Skulsuppaisarn, Grace Khuu, Thanh N. Nguyen, Danielle L. Rudler, Aleksandra Filipovska, Ralf B. Schittenhelm, Michael Lazarou
bioRxiv 2022.11.30.518286; doi: https://doi.org/10.1101/2022.11.30.518286

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