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Potent Immunogenicity and Broad-Spectrum Protection Potential of Microneedle Array Patch-Based COVID-19 DNA Vaccine Candidates Encoding Dimeric RBD Chimera of SARS-CoV and SARS-CoV-2 Variants

Feng Fan, Xin Zhang, Zhiyu Zhang, Yuan Ding, Limei Wang, Xin Xu, Yaying Pan, Fang-Yuan Gong, Lin Jiang, Lingyu Kang, Zhihua Kou, Gan Zhao, Bin Wang, Xiao-Ming Gao
doi: https://doi.org/10.1101/2022.12.01.518127
Feng Fan
1Advaccine Biopharmaceutics (Suzhou) Co. Ltd, Suzhou, China
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Xin Zhang
1Advaccine Biopharmaceutics (Suzhou) Co. Ltd, Suzhou, China
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Zhiyu Zhang
1Advaccine Biopharmaceutics (Suzhou) Co. Ltd, Suzhou, China
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Yuan Ding
1Advaccine Biopharmaceutics (Suzhou) Co. Ltd, Suzhou, China
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Limei Wang
1Advaccine Biopharmaceutics (Suzhou) Co. Ltd, Suzhou, China
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Xin Xu
1Advaccine Biopharmaceutics (Suzhou) Co. Ltd, Suzhou, China
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Yaying Pan
2School of Biological Science and Basic Medicine, Soochow University, Suzhou, China
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Fang-Yuan Gong
2School of Biological Science and Basic Medicine, Soochow University, Suzhou, China
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Lin Jiang
3Shenzhen Qinglan Biotechnology Co. Ltd., Shenzhen, China
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Lingyu Kang
3Shenzhen Qinglan Biotechnology Co. Ltd., Shenzhen, China
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Zhihua Kou
1Advaccine Biopharmaceutics (Suzhou) Co. Ltd, Suzhou, China
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Gan Zhao
1Advaccine Biopharmaceutics (Suzhou) Co. Ltd, Suzhou, China
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Bin Wang
1Advaccine Biopharmaceutics (Suzhou) Co. Ltd, Suzhou, China
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  • For correspondence: gaoxiaoming@advaccine.com bwang@advaccine.com
Xiao-Ming Gao
1Advaccine Biopharmaceutics (Suzhou) Co. Ltd, Suzhou, China
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  • For correspondence: gaoxiaoming@advaccine.com bwang@advaccine.com
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Posted December 02, 2022.
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Potent Immunogenicity and Broad-Spectrum Protection Potential of Microneedle Array Patch-Based COVID-19 DNA Vaccine Candidates Encoding Dimeric RBD Chimera of SARS-CoV and SARS-CoV-2 Variants
Feng Fan, Xin Zhang, Zhiyu Zhang, Yuan Ding, Limei Wang, Xin Xu, Yaying Pan, Fang-Yuan Gong, Lin Jiang, Lingyu Kang, Zhihua Kou, Gan Zhao, Bin Wang, Xiao-Ming Gao
bioRxiv 2022.12.01.518127; doi: https://doi.org/10.1101/2022.12.01.518127
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Potent Immunogenicity and Broad-Spectrum Protection Potential of Microneedle Array Patch-Based COVID-19 DNA Vaccine Candidates Encoding Dimeric RBD Chimera of SARS-CoV and SARS-CoV-2 Variants
Feng Fan, Xin Zhang, Zhiyu Zhang, Yuan Ding, Limei Wang, Xin Xu, Yaying Pan, Fang-Yuan Gong, Lin Jiang, Lingyu Kang, Zhihua Kou, Gan Zhao, Bin Wang, Xiao-Ming Gao
bioRxiv 2022.12.01.518127; doi: https://doi.org/10.1101/2022.12.01.518127

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