Podoplanin expression in fibroblasts determines lymph node architecture and adaptive immune function

Spyridon Makris; Yukti Hari-Gupta; Jesús A. Cantoral-Rebordinos; Victor G. Martinez; Harry L. Horsnell; Charlotte M. de Winde; Tanya Singh; Martina Jovancheva; Robin Kettler; Janos Kriston-Vizi; Sophie E. Acton

doi:10.1101/2022.12.01.518753

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Podoplanin expression in fibroblasts determines lymph node architecture and adaptive immune function

Spyridon Makris, Yukti Hari-Gupta, Jesús A. Cantoral-Rebordinos, Victor G. Martinez, Harry L. Horsnell, Charlotte M. de Winde, Tanya Singh, Martina Jovancheva, Robin Kettler, Janos Kriston-Vizi, View ORCID ProfileSophie E. Acton

doi: https://doi.org/10.1101/2022.12.01.518753

Spyridon Makris

1Stromal Immunology Group, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK

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Yukti Hari-Gupta

1Stromal Immunology Group, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK

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Jesús A. Cantoral-Rebordinos

1Stromal Immunology Group, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK

2Stem Cell and Human Development Laboratory, The Francis Crick Institute, 1 Midland Road, NW1 1AT

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Victor G. Martinez

1Stromal Immunology Group, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK

3Molecular Oncology Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain

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Harry L. Horsnell

1Stromal Immunology Group, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK

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Charlotte M. de Winde

1Stromal Immunology Group, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK

4Department for Molecular Cell Biology and Immunology, Amsterdam UMC, location VUmc, De Boelelaan 1108, 1081 HZ Amsterdam, Netherlands

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Tanya Singh

5Cell Signalling and Autophagy, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK

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Martina Jovancheva

1Stromal Immunology Group, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK

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Robin Kettler

5Cell Signalling and Autophagy, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK

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Janos Kriston-Vizi

6Bioinformatic group, Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK

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Sophie E. Acton

1Stromal Immunology Group, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK

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ORCID record for Sophie E. Acton
For correspondence: s.acton@ucl.ac.uk

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Podoplanin expression in fibroblasts determines lymph node architecture and adaptive immune function

bioRxiv 2022.12.01.518753; doi: https://doi.org/10.1101/2022.12.01.518753

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Podoplanin expression in fibroblasts determines lymph node architecture and adaptive immune function

bioRxiv 2022.12.01.518753; doi: https://doi.org/10.1101/2022.12.01.518753

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