Structure of a reversible amyloid fibril formed by the CPEB3 prion-like domain reveals a core sequence involved in translational regulation

Maria D. Flores; Michael R. Sawaya; David R. Boyer; Samantha Zink; Susanna Tovmasyan; Adrian Saucedo; Chih-Te Zee; Jorge Cardenas; Luana Fioriti; Jose A. Rodriguez

doi:10.1101/2022.12.07.519389

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Structure of a reversible amyloid fibril formed by the CPEB3 prion-like domain reveals a core sequence involved in translational regulation

View ORCID ProfileMaria D. Flores, View ORCID ProfileMichael R. Sawaya, View ORCID ProfileDavid R. Boyer, View ORCID ProfileSamantha Zink, Susanna Tovmasyan, Adrian Saucedo, View ORCID ProfileChih-Te Zee, Jorge Cardenas, View ORCID ProfileLuana Fioriti, View ORCID ProfileJose A. Rodriguez

doi: https://doi.org/10.1101/2022.12.07.519389

Maria D. Flores

1Department of Chemistry and Biochemistry; UCLA-DOE Institute for Genomics and Proteomics; STROBE, NSF Science and Technology Center; University of California, Los Angeles (UCLA); Los Angeles, CA 90095, USA

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For correspondence: jrodriguez@mbi.ucla.edu luana.fioriti@marionegri.it mflores@mbi.ucla.edu

Michael R. Sawaya

2Department of Biological Chemistry and Department of Chemistry and Biochemistry, University of California Los Angeles (UCLA), Howard Hughes Medical Institute (HHMI), UCLA-DOE Institute for Genomics and Proteomics, Los Angeles, CA 90095, USA

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David R. Boyer

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Samantha Zink

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Susanna Tovmasyan

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Adrian Saucedo

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Chih-Te Zee

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Jorge Cardenas

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Luana Fioriti

3Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milano MI, 20156, Italy

4Department of Neuroscience, Columbia University, New York, NY 10027, USA

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For correspondence: jrodriguez@mbi.ucla.edu luana.fioriti@marionegri.it mflores@mbi.ucla.edu

Jose A. Rodriguez

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For correspondence: jrodriguez@mbi.ucla.edu luana.fioriti@marionegri.it mflores@mbi.ucla.edu

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Structure of a reversible amyloid fibril formed by the CPEB3 prion-like domain reveals a core sequence involved in translational regulation

Maria D. Flores, Michael R. Sawaya, David R. Boyer, Samantha Zink, Susanna Tovmasyan, Adrian Saucedo, Chih-Te Zee, Jorge Cardenas, Luana Fioriti, Jose A. Rodriguez

bioRxiv 2022.12.07.519389; doi: https://doi.org/10.1101/2022.12.07.519389

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Structure of a reversible amyloid fibril formed by the CPEB3 prion-like domain reveals a core sequence involved in translational regulation

Maria D. Flores, Michael R. Sawaya, David R. Boyer, Samantha Zink, Susanna Tovmasyan, Adrian Saucedo, Chih-Te Zee, Jorge Cardenas, Luana Fioriti, Jose A. Rodriguez

bioRxiv 2022.12.07.519389; doi: https://doi.org/10.1101/2022.12.07.519389

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