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First gene-edited calf with reduced susceptibility to a major viral pathogen

View ORCID ProfileAspen M Workman, View ORCID ProfileMichael P Heaton, View ORCID ProfileBrian L Vander Ley, Dennis A Webster, Luke Sherry, Sabreena Larson, Theodore S Kalbfleisch, View ORCID ProfileGregory P Harhay, Erin E Jobman, Daniel F Carlson, View ORCID ProfileTad S Sonstegard
doi: https://doi.org/10.1101/2022.12.08.519336
Aspen M Workman
1US Meat Animal Research Center, United States Department of Agriculture (USDA), Agricultural Research Service (ARS), Clay Center, NE, 68933, USA
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  • ORCID record for Aspen M Workman
  • For correspondence: aspen.workman@usda.gov
Michael P Heaton
1US Meat Animal Research Center, United States Department of Agriculture (USDA), Agricultural Research Service (ARS), Clay Center, NE, 68933, USA
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Brian L Vander Ley
2University of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA
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Dennis A Webster
3Recombinetics Inc., Eagan, MN, 55121, USA
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Luke Sherry
3Recombinetics Inc., Eagan, MN, 55121, USA
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Sabreena Larson
3Recombinetics Inc., Eagan, MN, 55121, USA
4Acceligen Inc., Eagan, MN, 55121, USA
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Theodore S Kalbfleisch
5Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, Lexington, KY, 40506, USA
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Gregory P Harhay
1US Meat Animal Research Center, United States Department of Agriculture (USDA), Agricultural Research Service (ARS), Clay Center, NE, 68933, USA
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  • ORCID record for Gregory P Harhay
Erin E Jobman
2University of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA
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Daniel F Carlson
3Recombinetics Inc., Eagan, MN, 55121, USA
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Tad S Sonstegard
3Recombinetics Inc., Eagan, MN, 55121, USA
4Acceligen Inc., Eagan, MN, 55121, USA
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  • ORCID record for Tad S Sonstegard
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Article Information

doi 
https://doi.org/10.1101/2022.12.08.519336
History 
  • December 8, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. This article is a US Government work. It is not subject to copyright under 17 USC 105 and is also made available for use under a CC0 license.

Author Information

  1. Aspen M Workman1,*,
  2. Michael P Heaton1,
  3. Brian L Vander Ley2,
  4. Dennis A Webster3,
  5. Luke Sherry3,
  6. Sabreena Larson3,4,
  7. Theodore S Kalbfleisch5,
  8. Gregory P Harhay1,
  9. Erin E Jobman2,
  10. Daniel F Carlson3 and
  11. Tad S Sonstegard3,4
  1. 1US Meat Animal Research Center, United States Department of Agriculture (USDA), Agricultural Research Service (ARS), Clay Center, NE, 68933, USA
  2. 2University of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA
  3. 3Recombinetics Inc., Eagan, MN, 55121, USA
  4. 4Acceligen Inc., Eagan, MN, 55121, USA
  5. 5Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, Lexington, KY, 40506, USA
  1. ↵*Corresponding author: Aspen Workman, US Meat Animal Research Center, 844 Road 313, Spur 18 D, Clay Center, NE 68933, Phone: 402-762-4374, Email: aspen.workman{at}usda.gov
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Posted December 08, 2022.
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First gene-edited calf with reduced susceptibility to a major viral pathogen
Aspen M Workman, Michael P Heaton, Brian L Vander Ley, Dennis A Webster, Luke Sherry, Sabreena Larson, Theodore S Kalbfleisch, Gregory P Harhay, Erin E Jobman, Daniel F Carlson, Tad S Sonstegard
bioRxiv 2022.12.08.519336; doi: https://doi.org/10.1101/2022.12.08.519336
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First gene-edited calf with reduced susceptibility to a major viral pathogen
Aspen M Workman, Michael P Heaton, Brian L Vander Ley, Dennis A Webster, Luke Sherry, Sabreena Larson, Theodore S Kalbfleisch, Gregory P Harhay, Erin E Jobman, Daniel F Carlson, Tad S Sonstegard
bioRxiv 2022.12.08.519336; doi: https://doi.org/10.1101/2022.12.08.519336

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