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First gene-edited calf with reduced susceptibility to a major viral pathogen

View ORCID ProfileAspen M Workman, View ORCID ProfileMichael P Heaton, View ORCID ProfileBrian L Vander Ley, Dennis A Webster, Luke Sherry, Sabreena Larson, Theodore S Kalbfleisch, View ORCID ProfileGregory P Harhay, Erin E Jobman, Daniel F Carlson, View ORCID ProfileTad S Sonstegard
doi: https://doi.org/10.1101/2022.12.08.519336
Aspen M Workman
1US Meat Animal Research Center, United States Department of Agriculture (USDA), Agricultural Research Service (ARS), Clay Center, NE, 68933, USA
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  • ORCID record for Aspen M Workman
  • For correspondence: aspen.workman@usda.gov
Michael P Heaton
1US Meat Animal Research Center, United States Department of Agriculture (USDA), Agricultural Research Service (ARS), Clay Center, NE, 68933, USA
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Brian L Vander Ley
2University of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA
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Dennis A Webster
3Recombinetics Inc., Eagan, MN, 55121, USA
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Luke Sherry
3Recombinetics Inc., Eagan, MN, 55121, USA
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Sabreena Larson
3Recombinetics Inc., Eagan, MN, 55121, USA
4Acceligen Inc., Eagan, MN, 55121, USA
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Theodore S Kalbfleisch
5Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, Lexington, KY, 40506, USA
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Gregory P Harhay
1US Meat Animal Research Center, United States Department of Agriculture (USDA), Agricultural Research Service (ARS), Clay Center, NE, 68933, USA
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  • ORCID record for Gregory P Harhay
Erin E Jobman
2University of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA
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Daniel F Carlson
3Recombinetics Inc., Eagan, MN, 55121, USA
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Tad S Sonstegard
3Recombinetics Inc., Eagan, MN, 55121, USA
4Acceligen Inc., Eagan, MN, 55121, USA
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  • ORCID record for Tad S Sonstegard
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  • Table S1, Table S2, Table S3, Table S4, Fig. S1, Fig. S2, Fig. S3, Fig. S4, Fig. S5, Fig. S6[supplements/519336_file03.pdf]
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Posted December 08, 2022.
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First gene-edited calf with reduced susceptibility to a major viral pathogen
Aspen M Workman, Michael P Heaton, Brian L Vander Ley, Dennis A Webster, Luke Sherry, Sabreena Larson, Theodore S Kalbfleisch, Gregory P Harhay, Erin E Jobman, Daniel F Carlson, Tad S Sonstegard
bioRxiv 2022.12.08.519336; doi: https://doi.org/10.1101/2022.12.08.519336
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First gene-edited calf with reduced susceptibility to a major viral pathogen
Aspen M Workman, Michael P Heaton, Brian L Vander Ley, Dennis A Webster, Luke Sherry, Sabreena Larson, Theodore S Kalbfleisch, Gregory P Harhay, Erin E Jobman, Daniel F Carlson, Tad S Sonstegard
bioRxiv 2022.12.08.519336; doi: https://doi.org/10.1101/2022.12.08.519336

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