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- March 25, 2024.
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- Version 1 (December 15, 2022 - 18:40).
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
Author Information
- Irmgard U. Haussmann1,2,
- Thomas C. Dix1,
- David W. J. Mcquarrie1,
- Veronica Dezi1,
- Abdullah I. Hans1,
- Roland Arnold3,4,5 and
- Matthias Soller1,4,5
- 1School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom
- 2College of Life Science, Birmingham City University, Birmingham, B5 3TN, United Kingdom
- 3Institute of Cancer and Genomics Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom
- 4Birmingham Centre for Genome Biology, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom
- ↵*Corresponding authors m.soller{at}bham.ac.uk, R.Arnold.2{at}bham.ac.uk, Tel: +44 121 414 5905
Posted March 25, 2024.
sgRNA constraints and genetic limitations for efficient Cas9 genome editing to generate knock-outs
