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Multi-center integrated analysis of non-coding CRISPR screens
View ORCID ProfileDavid Yao, View ORCID ProfileJosh Tycko, View ORCID ProfileJin Woo Oh, View ORCID ProfileLexi R. Bounds, View ORCID ProfileSager J. Gosai, View ORCID ProfileLazaros Lataniotis, View ORCID ProfileAva Mackay-Smith, View ORCID ProfileBenjamin R. Doughty, View ORCID ProfileIdan Gabdank, View ORCID ProfileHenri Schmidt, View ORCID ProfileIngrid Youngworth, View ORCID ProfileKalina Andreeva, View ORCID ProfileXingjie Ren, View ORCID ProfileAlejandro Barrera, Yunhai Luo, View ORCID ProfileKeith Siklenka, View ORCID ProfileGalip Gürkan Yardımcı, The ENCODE4 Consortium, View ORCID ProfileRyan Tewhey, View ORCID ProfileAnshul Kundaje, View ORCID ProfileWilliam J. Greenleaf, Pardis C. Sabeti, View ORCID ProfileChristina Leslie, View ORCID ProfileYuri Pritykin, View ORCID ProfileJill E. Moore, View ORCID ProfileMichael A. Beer, View ORCID ProfileCharles A. Gersbach, View ORCID ProfileTimothy E. Reddy, View ORCID ProfileYin Shen, View ORCID ProfileJesse M. Engreitz, View ORCID ProfileMichael C. Bassik, View ORCID ProfileSteven K. Reilly
doi: https://doi.org/10.1101/2022.12.21.520137
David Yao
1Department of Genetics, Stanford University, Stanford, CA, USA
Josh Tycko
1Department of Genetics, Stanford University, Stanford, CA, USA
2Department of Neurobiology, Harvard Medical School, Boston, MA, USA
Jin Woo Oh
3Department of Biomedical Engineering and Department of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA
Lexi R. Bounds
4Department of Biomedical Engineering, Duke University, Durham, NC, USA
5Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA
Sager J. Gosai
6Broad Institute of Harvard & MIT, Cambridge, MA, USA
7Center for System Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA
8Harvard Graduate Program in Biological and Biomedical Science, Boston, MA, USA
Lazaros Lataniotis
9Institute for Human Genetics, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA
Ava Mackay-Smith
10Yale University, Department of Genetics, New Haven, CT, USA
11University Program in Genetics and Genomics, Duke University School of Medicine, Durham, NC, USA
Benjamin R. Doughty
1Department of Genetics, Stanford University, Stanford, CA, USA
Idan Gabdank
1Department of Genetics, Stanford University, Stanford, CA, USA
Henri Schmidt
12Department of Computer Science, Princeton University, Princeton, NJ, USA
13Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ingrid Youngworth
1Department of Genetics, Stanford University, Stanford, CA, USA
Kalina Andreeva
1Department of Genetics, Stanford University, Stanford, CA, USA
Xingjie Ren
9Institute for Human Genetics, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA
Alejandro Barrera
5Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA
14Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA
Yunhai Luo
1Department of Genetics, Stanford University, Stanford, CA, USA
Keith Siklenka
5Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA
14Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA
Galip Gürkan Yardımcı
15Knight Cancer Center, Oregon Health and Science University, Portland, OR, USA
Ryan Tewhey
16The Jackson Laboratory, Bar Harbor, ME, USA
Anshul Kundaje
1Department of Genetics, Stanford University, Stanford, CA, USA
17Department of Computer Science, Stanford University, Stanford, CA, USA
William J. Greenleaf
1Department of Genetics, Stanford University, Stanford, CA, USA
18Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA,, USA
19Department of Applied Physics, Stanford University, Stanford, CA, USA
20Chan Zuckerberg Biohub, San Francisco, CA, USA
Pardis C. Sabeti
6Broad Institute of Harvard & MIT, Cambridge, MA, USA
7Center for System Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA
21Howard Hughes Medical Institute; Chevy Chase, MD, USA
22Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health; Boston, MA, USA
Christina Leslie
13Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Yuri Pritykin
12Department of Computer Science, Princeton University, Princeton, NJ, USA
23Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ
Jill E. Moore
24Program in Bioinformatics and Integrative Biology, RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA
Michael A. Beer
3Department of Biomedical Engineering and Department of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA
Charles A. Gersbach
4Department of Biomedical Engineering, Duke University, Durham, NC, USA
5Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA
Timothy E. Reddy
5Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA
14Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA
Yin Shen
9Institute for Human Genetics, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA
25Department of Neurology, University of California, San Francisco, San Francisco, CA, USA
26Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA
Jesse M. Engreitz
1Department of Genetics, Stanford University, Stanford, CA, USA
27BASE Initiative, Betty Irene Moore Children’s Heart Center, Lucile Packard Children’s Hospital, Stanford, CA, USA
Michael C. Bassik
1Department of Genetics, Stanford University, Stanford, CA, USA
Steven K. Reilly
10Yale University, Department of Genetics, New Haven, CT, USA
Article usage
Posted December 22, 2022.
Multi-center integrated analysis of non-coding CRISPR screens
David Yao, Josh Tycko, Jin Woo Oh, Lexi R. Bounds, Sager J. Gosai, Lazaros Lataniotis, Ava Mackay-Smith, Benjamin R. Doughty, Idan Gabdank, Henri Schmidt, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Keith Siklenka, Galip Gürkan Yardımcı, The ENCODE4 Consortium, Ryan Tewhey, Anshul Kundaje, William J. Greenleaf, Pardis C. Sabeti, Christina Leslie, Yuri Pritykin, Jill E. Moore, Michael A. Beer, Charles A. Gersbach, Timothy E. Reddy, Yin Shen, Jesse M. Engreitz, Michael C. Bassik, Steven K. Reilly
bioRxiv 2022.12.21.520137; doi: https://doi.org/10.1101/2022.12.21.520137
Multi-center integrated analysis of non-coding CRISPR screens
David Yao, Josh Tycko, Jin Woo Oh, Lexi R. Bounds, Sager J. Gosai, Lazaros Lataniotis, Ava Mackay-Smith, Benjamin R. Doughty, Idan Gabdank, Henri Schmidt, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Keith Siklenka, Galip Gürkan Yardımcı, The ENCODE4 Consortium, Ryan Tewhey, Anshul Kundaje, William J. Greenleaf, Pardis C. Sabeti, Christina Leslie, Yuri Pritykin, Jill E. Moore, Michael A. Beer, Charles A. Gersbach, Timothy E. Reddy, Yin Shen, Jesse M. Engreitz, Michael C. Bassik, Steven K. Reilly
bioRxiv 2022.12.21.520137; doi: https://doi.org/10.1101/2022.12.21.520137
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