Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Identification of potential blood-derived extracellular vesicles biomarkers to diagnose and predict distant metastases in ER+ breast cancer patients

Zia Hamidi, Eduardo Tejero, Ronny Schmidt, Rod Tucker, Ana Pedro
doi: https://doi.org/10.1101/202291
Zia Hamidi
1Ana Pedro Laboratories, Ltd, 6 Pools Brook Park, Kingswood, Pools Brook Park, Kingswood, Hull, United Kingdom, HU7 3GE, Ph: +44 7465 853555, Email:
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: anapedrolaboratories@gmail.com
Eduardo Tejero
1Ana Pedro Laboratories, Ltd, 6 Pools Brook Park, Kingswood, Pools Brook Park, Kingswood, Hull, United Kingdom, HU7 3GE, Ph: +44 7465 853555, Email:
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: anapedrolaboratories@gmail.com
Ronny Schmidt
4Sciomics GmbH, Im Neuenheimer Feld 583, 69120 Heidelberg, Germany, Ph:+49 (0) 6221 4294833,
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: ronny.schmidt@sciomics.de
Rod Tucker
1Ana Pedro Laboratories, Ltd, 6 Pools Brook Park, Kingswood, Pools Brook Park, Kingswood, Hull, United Kingdom, HU7 3GE, Ph: +44 7465 853555, Email:
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: anacadavezpedro@hotmail.com rodtucker.tucker@gmail.com anapedrolaboratories@gmail.com
Ana Pedro
1Ana Pedro Laboratories, Ltd, 6 Pools Brook Park, Kingswood, Pools Brook Park, Kingswood, Hull, United Kingdom, HU7 3GE, Ph: +44 7465 853555, Email:
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: anacadavezpedro@hotmail.com rodtucker.tucker@gmail.com anapedrolaboratories@gmail.com
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Abstract

The objective of this study was to identify potential extracellular vesicles (EV) which might serve as biomarkers for predictive and diagnostic purposes in metastatic breast cancer. Plasma samples from 7 different metastatic and non-metastatic ER+ (estrogen receptor -positive) breast cancer patients were collected, EV were isolated and their protein content analyzed by mass spectrometry and FunRich analysis. In this study we found several putative plasma EV biomarkers for metastatic ER+ breast cancer prediction and diagnosis, such as serum amyloid A1, known to promote widespread metastasis in a breast cancer animal model.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Back to top
PreviousNext
Posted October 12, 2017.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Identification of potential blood-derived extracellular vesicles biomarkers to diagnose and predict distant metastases in ER+ breast cancer patients
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Identification of potential blood-derived extracellular vesicles biomarkers to diagnose and predict distant metastases in ER+ breast cancer patients
Zia Hamidi, Eduardo Tejero, Ronny Schmidt, Rod Tucker, Ana Pedro
bioRxiv 202291; doi: https://doi.org/10.1101/202291
Reddit logo Twitter logo Facebook logo LinkedIn logo Mendeley logo
Citation Tools
Identification of potential blood-derived extracellular vesicles biomarkers to diagnose and predict distant metastases in ER+ breast cancer patients
Zia Hamidi, Eduardo Tejero, Ronny Schmidt, Rod Tucker, Ana Pedro
bioRxiv 202291; doi: https://doi.org/10.1101/202291

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Cancer Biology
Subject Areas
All Articles
  • Animal Behavior and Cognition (4377)
  • Biochemistry (9568)
  • Bioengineering (7079)
  • Bioinformatics (24808)
  • Biophysics (12582)
  • Cancer Biology (9932)
  • Cell Biology (14307)
  • Clinical Trials (138)
  • Developmental Biology (7940)
  • Ecology (12087)
  • Epidemiology (2067)
  • Evolutionary Biology (15971)
  • Genetics (10910)
  • Genomics (14719)
  • Immunology (9855)
  • Microbiology (23610)
  • Molecular Biology (9466)
  • Neuroscience (50782)
  • Paleontology (369)
  • Pathology (1537)
  • Pharmacology and Toxicology (2675)
  • Physiology (4003)
  • Plant Biology (8650)
  • Scientific Communication and Education (1506)
  • Synthetic Biology (2388)
  • Systems Biology (6418)
  • Zoology (1345)