Article Information
History
- January 4, 2023.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
Author Information
- Jasmin Rees1,2,*,
- Gaurab Sarangi3,*,
- Qing Cheng4,*,
- Martin Floor5,6,*,
- Aida M Andrés2,
- Baldomero Oliva Miguel7,
- Jordi Villà-Freixa5,8,
- Elias SJ Arnér4,9 and
- Sergi Castellano1,10,**
- 1Great Ormond Street Institute of Child Health, University College London, London, United Kingdom
- 2Division of Biosciences, University College London, London, United Kingdom
- 3Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
- 4Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
- 5Department of Biosciences, Faculty of Sciences and Technology, Universitat de Vic - Universitat Central de Catalunya, Vic, Spain
- 6Barcelona Supercomputing Center (BSC), Barcelona, Spain
- 7Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain
- 8Institut de Recerca i Innovació en Ciències de la Vida i de la Salut a la Catalunya Central (IRIS-CC), Vic, Spain
- 9Department of Selenoprotein Research, National Institute of Oncology, Budapest, Hungary
- 10UCL Genomics, University College London, London, United Kingdom
- ↵** Corresponding author; email: s.castellano{at}ucl.ac.uk
↵* These authors contributed equally.
Posted January 04, 2023.
Ancient loss of catalytic selenocysteine spurred convergent adaptation in a mammalian oxidoreductase
