AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics

Aanchal Mongia; Diane C. Saunders; Yue J. Wang; Marcela Brissova; Alvin C. Powers; Klaus H. Kaestner; Golnaz Vahedi; Ali Naji; Gregory W. Schwartz; Robert B. Faryabi

doi:10.1101/2023.01.15.524135

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AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics

Aanchal Mongia, Diane C. Saunders, Yue J. Wang, Marcela Brissova, Alvin C. Powers, Klaus H. Kaestner, Golnaz Vahedi, Ali Naji, Gregory W. Schwartz, Robert B. Faryabi

doi: https://doi.org/10.1101/2023.01.15.524135

Aanchal Mongia

1Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

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Diane C. Saunders

7Department of Medicine, Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University School of Medicine, Nashville, TN, USA

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Yue J. Wang

3Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

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Marcela Brissova

7Department of Medicine, Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University School of Medicine, Nashville, TN, USA

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Alvin C. Powers

6Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, USA

7Department of Medicine, Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University School of Medicine, Nashville, TN, USA

8VA Tennessee Valley Healthcare System, Nashville, Tennessee, 37212, USA

10Human Pancreas Analysis Program Consortium

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Klaus H. Kaestner

3Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

4Epigenetics Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

5Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

10Human Pancreas Analysis Program Consortium

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Golnaz Vahedi

3Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

4Epigenetics Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

5Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

10Human Pancreas Analysis Program Consortium

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Ali Naji

2Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

5Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

10Human Pancreas Analysis Program Consortium

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Gregory W. Schwartz

9Princess Margaret Cancer Center, University Health Network, Toronto, ON, Canada

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For correspondence: Gregory.Schwartz@uhnresearch.ca faryabi@pennmedicine.upenn.edu

Robert B. Faryabi

1Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

4Epigenetics Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

10Human Pancreas Analysis Program Consortium

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For correspondence: Gregory.Schwartz@uhnresearch.ca faryabi@pennmedicine.upenn.edu

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AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics

Aanchal Mongia, Diane C. Saunders, Yue J. Wang, Marcela Brissova, Alvin C. Powers, Klaus H. Kaestner, Golnaz Vahedi, Ali Naji, Gregory W. Schwartz, Robert B. Faryabi

bioRxiv 2023.01.15.524135; doi: https://doi.org/10.1101/2023.01.15.524135

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AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics

Aanchal Mongia, Diane C. Saunders, Yue J. Wang, Marcela Brissova, Alvin C. Powers, Klaus H. Kaestner, Golnaz Vahedi, Ali Naji, Gregory W. Schwartz, Robert B. Faryabi

bioRxiv 2023.01.15.524135; doi: https://doi.org/10.1101/2023.01.15.524135

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