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Comprehensive longitudinal study of home-cage activity, including climbing, reveals new complex phenotypic profile in the N171-82Q HD mouse model with implications for refined preclinical studies

Rasneer S. Bains, Hamish Forrest, Rowland R. Sillito, J. Douglas Armstrong, Michelle Stewart, Patrick M. Nolan, Sara E. Wells
doi: https://doi.org/10.1101/2023.01.19.524755

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doi 
https://doi.org/10.1101/2023.01.19.524755
History 
  • January 20, 2023.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Rasneer S. Bains1,*,
  2. Hamish Forrest1,
  3. Rowland R. Sillito3,
  4. J. Douglas Armstrong3,4,
  5. Michelle Stewart1,
  6. Patrick M. Nolan2 and
  7. Sara E. Wells1
  1. 1Mary Lyon Centre at Medical Research Council, Harwell, Oxfordshire, UK
  2. 2Medical Research Council, Harwell Science Campus, UK
  3. 3Actual Analytics Ltd., Edinburgh, UK
  4. 4School of Informatics, University of Edinburgh, UK
  1. ↵*Correspondence:
    Rasneer S Bains, r.bains{at}har.mrc.ac.uk
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Posted January 20, 2023.
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Comprehensive longitudinal study of home-cage activity, including climbing, reveals new complex phenotypic profile in the N171-82Q HD mouse model with implications for refined preclinical studies
Rasneer S. Bains, Hamish Forrest, Rowland R. Sillito, J. Douglas Armstrong, Michelle Stewart, Patrick M. Nolan, Sara E. Wells
bioRxiv 2023.01.19.524755; doi: https://doi.org/10.1101/2023.01.19.524755
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