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Comprehensive longitudinal study of home-cage activity, including climbing, reveals new complex phenotypic profile in the N171-82Q HD mouse model with implications for refined preclinical studies
View ORCID ProfileRasneer S. Bains, Hamish Forrest, Rowland R. Sillito, J. Douglas Armstrong, Michelle Stewart, View ORCID ProfilePatrick M. Nolan, View ORCID ProfileSara E. Wells
doi: https://doi.org/10.1101/2023.01.19.524755
Rasneer S. Bains
1Mary Lyon Centre at Medical Research Council, Harwell, Oxfordshire, UK
Hamish Forrest
1Mary Lyon Centre at Medical Research Council, Harwell, Oxfordshire, UK
Rowland R. Sillito
3Actual Analytics Ltd., Edinburgh, UK
J. Douglas Armstrong
3Actual Analytics Ltd., Edinburgh, UK
4School of Informatics, University of Edinburgh, UK
Michelle Stewart
1Mary Lyon Centre at Medical Research Council, Harwell, Oxfordshire, UK
Patrick M. Nolan
2Medical Research Council, Harwell Science Campus, UK
Sara E. Wells
1Mary Lyon Centre at Medical Research Council, Harwell, Oxfordshire, UK
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Posted January 20, 2023.
Comprehensive longitudinal study of home-cage activity, including climbing, reveals new complex phenotypic profile in the N171-82Q HD mouse model with implications for refined preclinical studies
Rasneer S. Bains, Hamish Forrest, Rowland R. Sillito, J. Douglas Armstrong, Michelle Stewart, Patrick M. Nolan, Sara E. Wells
bioRxiv 2023.01.19.524755; doi: https://doi.org/10.1101/2023.01.19.524755
Comprehensive longitudinal study of home-cage activity, including climbing, reveals new complex phenotypic profile in the N171-82Q HD mouse model with implications for refined preclinical studies
Rasneer S. Bains, Hamish Forrest, Rowland R. Sillito, J. Douglas Armstrong, Michelle Stewart, Patrick M. Nolan, Sara E. Wells
bioRxiv 2023.01.19.524755; doi: https://doi.org/10.1101/2023.01.19.524755
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