Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome

Tianyang Yan; Ashley R. Julio; Miranda Villanueva; Anthony E. Jones; Andréa B. Ball; Lisa M. Boatner; Alexandra C. Turmon; Stephanie L. Yen; Heta S. Desai; Ajit S. Divakaruni; Keriann M. Backus

doi:10.1101/2023.01.22.525042

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Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome

Tianyang Yan, Ashley R. Julio, Miranda Villanueva, Anthony E. Jones, Andréa B. Ball, Lisa M. Boatner, Alexandra C. Turmon, Stephanie L. Yen, Heta S. Desai, Ajit S. Divakaruni, View ORCID ProfileKeriann M. Backus

doi: https://doi.org/10.1101/2023.01.22.525042

Tianyang Yan

1Biological Chemistry Department, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA

2Department of Chemistry and Biochemistry, UCLA, Los Angeles, CA, 90095, USA

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Ashley R. Julio

1Biological Chemistry Department, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA

2Department of Chemistry and Biochemistry, UCLA, Los Angeles, CA, 90095, USA

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Miranda Villanueva

1Biological Chemistry Department, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA

4Molecular Biology Institute, UCLA, Los Angeles, CA, 90095, USA

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Anthony E. Jones

3Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA

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Andréa B. Ball

3Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA

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Lisa M. Boatner

1Biological Chemistry Department, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA

2Department of Chemistry and Biochemistry, UCLA, Los Angeles, CA, 90095, USA

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Alexandra C. Turmon

1Biological Chemistry Department, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA

2Department of Chemistry and Biochemistry, UCLA, Los Angeles, CA, 90095, USA

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Stephanie L. Yen

1Biological Chemistry Department, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA

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Heta S. Desai

1Biological Chemistry Department, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA

4Molecular Biology Institute, UCLA, Los Angeles, CA, 90095, USA

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Ajit S. Divakaruni

3Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA

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Keriann M. Backus

1Biological Chemistry Department, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA

2Department of Chemistry and Biochemistry, UCLA, Los Angeles, CA, 90095, USA

4Molecular Biology Institute, UCLA, Los Angeles, CA, 90095, USA

5DOE Institute for Genomics and Proteomics, UCLA, Los Angeles, CA, 90095, USA

6Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA, 90095, USA

7Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA, Los Angeles, CA, 90095, USA

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ORCID record for Keriann M. Backus
For correspondence: kbackus@mednet.ucla.edu

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Supplementary Information[supplements/525042_file02.pdf]
Table S1[supplements/525042_file03.xlsx]
Table S2[supplements/525042_file04.xlsx]
Table S3[supplements/525042_file05.xlsx]
Table S4[supplements/525042_file06.xlsx]
Table S5[supplements/525042_file07.xlsx]

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Posted January 31, 2023.

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Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome

Tianyang Yan, Ashley R. Julio, Miranda Villanueva, Anthony E. Jones, Andréa B. Ball, Lisa M. Boatner, Alexandra C. Turmon, Stephanie L. Yen, Heta S. Desai, Ajit S. Divakaruni, Keriann M. Backus

bioRxiv 2023.01.22.525042; doi: https://doi.org/10.1101/2023.01.22.525042

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Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome

Tianyang Yan, Ashley R. Julio, Miranda Villanueva, Anthony E. Jones, Andréa B. Ball, Lisa M. Boatner, Alexandra C. Turmon, Stephanie L. Yen, Heta S. Desai, Ajit S. Divakaruni, Keriann M. Backus

bioRxiv 2023.01.22.525042; doi: https://doi.org/10.1101/2023.01.22.525042

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