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Androgen aggravates aortic aneurysms via suppressing PD-1 in mice

Xufang Mu, Shu Liu, Zhuoran Wang, Kai Jiang, Tim McClintock, Arnold J. Stromberg, Alejandro V. Tezanos, Eugene S Lee, John A. Curci, Ming C Gong, View ORCID ProfileZhenheng Guo
doi: https://doi.org/10.1101/2023.01.22.525073
Xufang Mu
1Departments of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY
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Shu Liu
2Departments of Physiology, University of Kentucky, Lexington, KY
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Zhuoran Wang
1Departments of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY
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Kai Jiang
2Departments of Physiology, University of Kentucky, Lexington, KY
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Tim McClintock
2Departments of Physiology, University of Kentucky, Lexington, KY
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Arnold J. Stromberg
3Departments of Statistics, University of Kentucky, Lexington, KY
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Alejandro V. Tezanos
3Departments of Statistics, University of Kentucky, Lexington, KY
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Eugene S Lee
4Department of Research, Sacramento VA Medical Center, Mather, CA
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John A. Curci
5Department of Vascular Surgery, Vanderbilt University, Nashville, TN
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Ming C Gong
2Departments of Physiology, University of Kentucky, Lexington, KY
6Departments of Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY
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  • For correspondence: ming.gong@uky.edu zguo2@uky.edu
Zhenheng Guo
1Departments of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY
6Departments of Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY
7Department of Research, Lexington Veterans Affairs Medical Center, Lexington, KY, USA
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  • ORCID record for Zhenheng Guo
  • For correspondence: ming.gong@uky.edu zguo2@uky.edu
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Article Information

doi 
https://doi.org/10.1101/2023.01.22.525073
History 
  • January 22, 2023.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Xufang Mu1,
  2. Shu Liu2,
  3. Zhuoran Wang1,
  4. Kai Jiang2,
  5. Tim McClintock2,
  6. Arnold J. Stromberg3,
  7. Alejandro V. Tezanos3,
  8. Eugene S Lee4,
  9. John A. Curci5,
  10. Ming C Gong2,6,* and
  11. Zhenheng Guo1,6,7,*
  1. 1Departments of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY
  2. 2Departments of Physiology, University of Kentucky, Lexington, KY
  3. 3Departments of Statistics, University of Kentucky, Lexington, KY
  4. 6Departments of Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY
  5. 4Department of Research, Sacramento VA Medical Center, Mather, CA
  6. 5Department of Vascular Surgery, Vanderbilt University, Nashville, TN
  7. 7Department of Research, Lexington Veterans Affairs Medical Center, Lexington, KY, USA
  1. ↵*To whom correspondence should be addressed:
    Ming C. Gong, Ph.D., 509 Wethington Building, 900 South Limestone Street, Lexington, KY 40536, Phone: (859)218-1361, Email: ming.gong{at}uky.edu, Zhenheng Guo, Ph.D., 515 Wethington Building, 900 South Limestone Street, Lexington, KY 40536, Phone: (859)218-1416, email: zguo2{at}uky.edu
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Posted January 22, 2023.
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Androgen aggravates aortic aneurysms via suppressing PD-1 in mice
Xufang Mu, Shu Liu, Zhuoran Wang, Kai Jiang, Tim McClintock, Arnold J. Stromberg, Alejandro V. Tezanos, Eugene S Lee, John A. Curci, Ming C Gong, Zhenheng Guo
bioRxiv 2023.01.22.525073; doi: https://doi.org/10.1101/2023.01.22.525073
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Androgen aggravates aortic aneurysms via suppressing PD-1 in mice
Xufang Mu, Shu Liu, Zhuoran Wang, Kai Jiang, Tim McClintock, Arnold J. Stromberg, Alejandro V. Tezanos, Eugene S Lee, John A. Curci, Ming C Gong, Zhenheng Guo
bioRxiv 2023.01.22.525073; doi: https://doi.org/10.1101/2023.01.22.525073

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