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Pan-cancer Proteomics Analysis to Identify Tumor-Enriched and Highly Expressed Cell Surface Antigens as Potential Targets for Cancer Therapeutics

View ORCID ProfileJixin Wang, Wen Yu, Rachel D’Anna, Anna Przybyla, Matt Wilson, Matthew Sung, John Bullen, Elaine Hurt, Gina DAngelo, Ben Sidders, Zhongwu Lai, Wenyan Zhong
doi: https://doi.org/10.1101/2023.01.23.525265
Jixin Wang
1Oncology Data Science, AstraZeneca, Gaithersburg, MD
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  • ORCID record for Jixin Wang
Wen Yu
2Data Science and AI, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD
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Rachel D’Anna
1Oncology Data Science, AstraZeneca, Gaithersburg, MD
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Anna Przybyla
3Immune-oncology Discovery, AstraZeneca, Cambridge, UK
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Matt Wilson
4Early TDE Discovery, AstraZeneca, Cambridge, UK
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Matthew Sung
3Immune-oncology Discovery, AstraZeneca, Cambridge, UK
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John Bullen
5Early TTD Discovery, AstraZeneca, Cambridge, UK
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Elaine Hurt
5Early TTD Discovery, AstraZeneca, Cambridge, UK
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Gina DAngelo
6Late Oncology Statistics, Oncology R&D, AstraZeneca, Gaithersburg, MD
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Ben Sidders
7Oncology Data Science, Oncology R&D, AstraZeneca, Cambridge, UK
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Zhongwu Lai
8Oncology Data Science, Oncology R&D, AstraZeneca, Waltham, MA
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Wenyan Zhong
9Oncology Data Science, Oncology R&D, AstraZeneca, New York, NY
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  • For correspondence: wenyan.zhong@astrazeneca.com
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Article Information

doi 
https://doi.org/10.1101/2023.01.23.525265
History 
  • January 23, 2023.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Jixin Wang1,
  2. Wen Yu2,
  3. Rachel D’Anna1,
  4. Anna Przybyla3,
  5. Matt Wilson4,
  6. Matthew Sung3,
  7. John Bullen5,
  8. Elaine Hurt5,
  9. Gina DAngelo6,
  10. Ben Sidders7,
  11. Zhongwu Lai8 and
  12. Wenyan Zhong9,*
  1. 1Oncology Data Science, AstraZeneca, Gaithersburg, MD
  2. 2Data Science and AI, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD
  3. 3Immune-oncology Discovery, AstraZeneca, Cambridge, UK
  4. 4Early TDE Discovery, AstraZeneca, Cambridge, UK
  5. 5Early TTD Discovery, AstraZeneca, Cambridge, UK
  6. 6Late Oncology Statistics, Oncology R&D, AstraZeneca, Gaithersburg, MD
  7. 7Oncology Data Science, Oncology R&D, AstraZeneca, Cambridge, UK
  8. 8Oncology Data Science, Oncology R&D, AstraZeneca, Waltham, MA
  9. 9Oncology Data Science, Oncology R&D, AstraZeneca, New York, NY
  1. ↵*Corresponding author:
    Wenyan Zhong, AstraZeneca, One MedImmune Way, Gaithersburg, MD 20878, USA, Phone: (301) 398-4209, Fax: (301) 398-9000, E-mail: wenyan.zhong{at}astrazeneca.com
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Posted January 23, 2023.
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Pan-cancer Proteomics Analysis to Identify Tumor-Enriched and Highly Expressed Cell Surface Antigens as Potential Targets for Cancer Therapeutics
Jixin Wang, Wen Yu, Rachel D’Anna, Anna Przybyla, Matt Wilson, Matthew Sung, John Bullen, Elaine Hurt, Gina DAngelo, Ben Sidders, Zhongwu Lai, Wenyan Zhong
bioRxiv 2023.01.23.525265; doi: https://doi.org/10.1101/2023.01.23.525265
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Pan-cancer Proteomics Analysis to Identify Tumor-Enriched and Highly Expressed Cell Surface Antigens as Potential Targets for Cancer Therapeutics
Jixin Wang, Wen Yu, Rachel D’Anna, Anna Przybyla, Matt Wilson, Matthew Sung, John Bullen, Elaine Hurt, Gina DAngelo, Ben Sidders, Zhongwu Lai, Wenyan Zhong
bioRxiv 2023.01.23.525265; doi: https://doi.org/10.1101/2023.01.23.525265

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