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Genetic perturbation of mitochondrial function reveals functional role for specific mitonuclear genes, metabolites and pathways that regulate lifespan
Cheryl Zi Jin Phua, Xiaqing Zhao, Lesly Turcios-Hernandez, Morrigan McKernan, Morteza Abyadeh, Siming Ma, Daniel Promislow, Matt Kaeberlein, Alaattin Kaya
doi: https://doi.org/10.1101/2023.01.26.525799
Cheryl Zi Jin Phua
1Genome Institute of Singapore, Agency for Science, Technology, and Research (A* STAR), Singapore, Singapore
Xiaqing Zhao
2Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA
Lesly Turcios-Hernandez
3Department of Biology, Virginia Commonwealth University, Richmond, VA 23284 USA
Morrigan McKernan
3Department of Biology, Virginia Commonwealth University, Richmond, VA 23284 USA
Morteza Abyadeh
3Department of Biology, Virginia Commonwealth University, Richmond, VA 23284 USA
Siming Ma
1Genome Institute of Singapore, Agency for Science, Technology, and Research (A* STAR), Singapore, Singapore
Daniel Promislow
2Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA
4Department of Biology, University of Washington, Seattle, WA 98195, USA
Matt Kaeberlein
2Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA
Alaattin Kaya
3Department of Biology, Virginia Commonwealth University, Richmond, VA 23284 USA
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Posted January 27, 2023.
Genetic perturbation of mitochondrial function reveals functional role for specific mitonuclear genes, metabolites and pathways that regulate lifespan
Cheryl Zi Jin Phua, Xiaqing Zhao, Lesly Turcios-Hernandez, Morrigan McKernan, Morteza Abyadeh, Siming Ma, Daniel Promislow, Matt Kaeberlein, Alaattin Kaya
bioRxiv 2023.01.26.525799; doi: https://doi.org/10.1101/2023.01.26.525799
Genetic perturbation of mitochondrial function reveals functional role for specific mitonuclear genes, metabolites and pathways that regulate lifespan
Cheryl Zi Jin Phua, Xiaqing Zhao, Lesly Turcios-Hernandez, Morrigan McKernan, Morteza Abyadeh, Siming Ma, Daniel Promislow, Matt Kaeberlein, Alaattin Kaya
bioRxiv 2023.01.26.525799; doi: https://doi.org/10.1101/2023.01.26.525799
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