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The fitness effects of codon composition of the horizontally transferred antibiotic resistance genes intensify at sub-lethal antibiotic levels

Michael Shaferman, Melis Gensel, Noga Alon, Khawla Alasad, Barak Rotblat, Adrian W.R. Serohijos, Lital Alfonta, Shimon Bershtein
doi: https://doi.org/10.1101/2023.02.03.526952

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doi 
https://doi.org/10.1101/2023.02.03.526952
History 
  • February 3, 2023.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Michael Shaferman1,
  2. Melis Gensel2,
  3. Noga Alon1,
  4. Khawla Alasad1,
  5. Barak Rotblat3,1,
  6. Adrian W.R. Serohijos2,4,
  7. Lital Alfonta5,1 and
  8. Shimon Bershtein1,*
  1. 1Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
  2. 2Departement de Biochimie, Universite de Montreal, Quebec, Canada
  3. 3National Institute for Biotechnology in the Negev (NIBN), Beer-Sheva, Israel
  4. 4Centre Robert-Cedergren en Bio-informatique et Genomique, Universite de Montreal, Quebec, Canada
  5. 5Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, Israel
  1. ↵*Corresponding author: E-mail: shimonb{at}bgu.ac.il
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Posted February 03, 2023.
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The fitness effects of codon composition of the horizontally transferred antibiotic resistance genes intensify at sub-lethal antibiotic levels
Michael Shaferman, Melis Gensel, Noga Alon, Khawla Alasad, Barak Rotblat, Adrian W.R. Serohijos, Lital Alfonta, Shimon Bershtein
bioRxiv 2023.02.03.526952; doi: https://doi.org/10.1101/2023.02.03.526952
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