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Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers

Alexander Baryshev, Alyssa La Fleur, Benjamin Groves, Cirstyn Michel, David Baker, Ajasja Ljubetič, View ORCID ProfileGeorg Seelig
doi: https://doi.org/10.1101/2023.02.08.527770
Alexander Baryshev
1Department of Electrical & Computer Engineering, University of Washington, Seattle, WA 98195, USA
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Alyssa La Fleur
2Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA 98195, USA
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Benjamin Groves
1Department of Electrical & Computer Engineering, University of Washington, Seattle, WA 98195, USA
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Cirstyn Michel
3Department of Bioengineering, University of Washington, Seattle, WA 98195, USA
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David Baker
4Department of Biochemistry, University of Washington, Seattle, WA 98195, USA
5Institute for Protein Design, University of Washington, Seattle, WA 98195, USA
6Department of Bioengineering, University of Washington, Seattle, WA, USA
7Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA
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Ajasja Ljubetič
4Department of Biochemistry, University of Washington, Seattle, WA 98195, USA
5Institute for Protein Design, University of Washington, Seattle, WA 98195, USA
8Department for Synthetic Biology and Immunology, National Institute of Chemistry, Ljubljana SI-1000, Slovenia
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  • For correspondence: gseelig@uw.edu ajasja.ljubetic@gmail.com
Georg Seelig
1Department of Electrical & Computer Engineering, University of Washington, Seattle, WA 98195, USA
2Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA 98195, USA
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  • ORCID record for Georg Seelig
  • For correspondence: gseelig@uw.edu ajasja.ljubetic@gmail.com
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Posted February 09, 2023.
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Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers
Alexander Baryshev, Alyssa La Fleur, Benjamin Groves, Cirstyn Michel, David Baker, Ajasja Ljubetič, Georg Seelig
bioRxiv 2023.02.08.527770; doi: https://doi.org/10.1101/2023.02.08.527770
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Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers
Alexander Baryshev, Alyssa La Fleur, Benjamin Groves, Cirstyn Michel, David Baker, Ajasja Ljubetič, Georg Seelig
bioRxiv 2023.02.08.527770; doi: https://doi.org/10.1101/2023.02.08.527770

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