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Mixed IgG Fc immune complexes exhibit blended binding profiles and refine FcR affinity estimates
Zhixin Cyrillus Tan, View ORCID ProfileAnja Lux, View ORCID ProfileMarkus Biburger, Prabha Varghese, Stephen Lees, View ORCID ProfileFalk Nimmerjahn, View ORCID ProfileAaron S. Meyer
doi: https://doi.org/10.1101/2023.02.15.528730
Zhixin Cyrillus Tan
1Bioinformatics Interdepartmental Program, University of California, Los Angeles (UCLA)
Anja Lux
2Department of Genetics, Friedrich-Alexander-University of Erlangen-Nürnberg
Markus Biburger
2Department of Genetics, Friedrich-Alexander-University of Erlangen-Nürnberg
Prabha Varghese
2Department of Genetics, Friedrich-Alexander-University of Erlangen-Nürnberg
Stephen Lees
3Department of Bioengineering, UCLA
Falk Nimmerjahn
2Department of Genetics, Friedrich-Alexander-University of Erlangen-Nürnberg
Aaron S. Meyer
1Bioinformatics Interdepartmental Program, University of California, Los Angeles (UCLA)
3Department of Bioengineering, UCLA
4Jonsson Comprehensive Cancer Center, UCLA
5Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA
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Posted February 15, 2023.
Mixed IgG Fc immune complexes exhibit blended binding profiles and refine FcR affinity estimates
Zhixin Cyrillus Tan, Anja Lux, Markus Biburger, Prabha Varghese, Stephen Lees, Falk Nimmerjahn, Aaron S. Meyer
bioRxiv 2023.02.15.528730; doi: https://doi.org/10.1101/2023.02.15.528730
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