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Cardinal v3 - a versatile open source software for mass spectrometry imaging analysis

Kylie Ariel Bemis, View ORCID ProfileMelanie Christine Föll, View ORCID ProfileDan Guo, Sai Srikanth Lakkimsetty, View ORCID ProfileOlga Vitek
doi: https://doi.org/10.1101/2023.02.20.529280
Kylie Ariel Bemis
1Khoury College of Computer Sciences, Northeastern University, Boston, USA
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Melanie Christine Föll
1Khoury College of Computer Sciences, Northeastern University, Boston, USA
2Institute of Surgical Pathology, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany
3German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany
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Dan Guo
1Khoury College of Computer Sciences, Northeastern University, Boston, USA
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Sai Srikanth Lakkimsetty
1Khoury College of Computer Sciences, Northeastern University, Boston, USA
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Olga Vitek
1Khoury College of Computer Sciences, Northeastern University, Boston, USA
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  • ORCID record for Olga Vitek
  • For correspondence: o.vitek@northeastern.edu
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Abstract

Cardinal v3 is an open source software for reproducible analysis of mass spectrometry imaging experiments. A major update from its previous versions, Cardinal v3 supports most mass spectrometry imaging workflows. Its analytical capabilities include advanced data processing such as mass re-calibration, advanced statistical analyses such as single-ion segmentation and rough annotation-based classification, and memory-efficient analyses of large-scale multi-tissue experiments.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
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Posted February 21, 2023.
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Cardinal v3 - a versatile open source software for mass spectrometry imaging analysis
Kylie Ariel Bemis, Melanie Christine Föll, Dan Guo, Sai Srikanth Lakkimsetty, Olga Vitek
bioRxiv 2023.02.20.529280; doi: https://doi.org/10.1101/2023.02.20.529280
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Cardinal v3 - a versatile open source software for mass spectrometry imaging analysis
Kylie Ariel Bemis, Melanie Christine Föll, Dan Guo, Sai Srikanth Lakkimsetty, Olga Vitek
bioRxiv 2023.02.20.529280; doi: https://doi.org/10.1101/2023.02.20.529280

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