Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease

Angel D’Oliviera; Xuhang Dai; Saba Mottaghinia; Evan P. Geissler; Lucie Etienne; Yingkai Zhang; Jeffrey S. Mugridge

doi:10.1101/2023.02.20.529306

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Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease

Angel D’Oliviera, Xuhang Dai, Saba Mottaghinia, Evan P. Geissler, View ORCID ProfileLucie Etienne, View ORCID ProfileYingkai Zhang, View ORCID ProfileJeffrey S. Mugridge

doi: https://doi.org/10.1101/2023.02.20.529306

Angel D’Oliviera

1Department of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716

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Xuhang Dai

2Department of Chemistry, New York University, New York, NY 10003

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Saba Mottaghinia

3CIRI (Centre International de Recherche en Infectiologie), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007 Lyon, France

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Evan P. Geissler

1Department of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716

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Lucie Etienne

3CIRI (Centre International de Recherche en Infectiologie), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007 Lyon, France

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ORCID record for Lucie Etienne

Yingkai Zhang

2Department of Chemistry, New York University, New York, NY 10003

4Simons Center for Computational Physical Chemistry at New York University, New York, NY 10003

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Jeffrey S. Mugridge

1Department of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716

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For correspondence: mugridge@udel.edu

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Posted February 21, 2023.

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Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease

Angel D’Oliviera, Xuhang Dai, Saba Mottaghinia, Evan P. Geissler, Lucie Etienne, Yingkai Zhang, Jeffrey S. Mugridge

bioRxiv 2023.02.20.529306; doi: https://doi.org/10.1101/2023.02.20.529306

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Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease

Angel D’Oliviera, Xuhang Dai, Saba Mottaghinia, Evan P. Geissler, Lucie Etienne, Yingkai Zhang, Jeffrey S. Mugridge

bioRxiv 2023.02.20.529306; doi: https://doi.org/10.1101/2023.02.20.529306

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