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Epilepsy-associated SCN2A (NaV1.2) Variants Exhibit Diverse and Complex Functional Properties

Christopher H. Thompson, Franck Potet, Tatiana V. Abramova, Jean-Marc DeKeyser, Nora F. Ghabra, Carlos G. Vanoye, John Millichap, View ORCID ProfileAlfred L. George Jr.
doi: https://doi.org/10.1101/2023.02.23.529757
Christopher H. Thompson
1Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA
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Franck Potet
1Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA
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Tatiana V. Abramova
1Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA
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Jean-Marc DeKeyser
1Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA
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Nora F. Ghabra
1Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA
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Carlos G. Vanoye
1Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA
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John Millichap
2Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA
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Alfred L. George Jr.
1Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA
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  • ORCID record for Alfred L. George Jr.
  • For correspondence: al.george@northwestern.edu
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Article Information

doi 
https://doi.org/10.1101/2023.02.23.529757
History 
  • February 23, 2023.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.

Author Information

  1. Christopher H. Thompson1,‡,
  2. Franck Potet1,*,‡,
  3. Tatiana V. Abramova1,
  4. Jean-Marc DeKeyser1,
  5. Nora F. Ghabra1,
  6. Carlos G. Vanoye1,
  7. John Millichap2 and
  8. Alfred L. George Jr.1,†
  1. 1Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA
  2. 2Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA
  1. ↵†Correspondence:
    al.george{at}northwestern.edu
  1. ↵‡ There authors contributed equally to this work.

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Posted February 23, 2023.
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Epilepsy-associated SCN2A (NaV1.2) Variants Exhibit Diverse and Complex Functional Properties
Christopher H. Thompson, Franck Potet, Tatiana V. Abramova, Jean-Marc DeKeyser, Nora F. Ghabra, Carlos G. Vanoye, John Millichap, Alfred L. George Jr.
bioRxiv 2023.02.23.529757; doi: https://doi.org/10.1101/2023.02.23.529757
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Epilepsy-associated SCN2A (NaV1.2) Variants Exhibit Diverse and Complex Functional Properties
Christopher H. Thompson, Franck Potet, Tatiana V. Abramova, Jean-Marc DeKeyser, Nora F. Ghabra, Carlos G. Vanoye, John Millichap, Alfred L. George Jr.
bioRxiv 2023.02.23.529757; doi: https://doi.org/10.1101/2023.02.23.529757

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