Generation of a SARS-CoV-2 reverse genetics system and novel human lung cell lines that exhibit high virus-induced cytopathology

Juveriya Qamar Khan; Megha Rohamare; Karthic Rajamanickam; Kalpana K Bhanumathy; Jocelyne Lew; Anil Kumar; Darryl Falzarano; Franco J Vizeacoumar; Joyce A Wilson

doi:10.1101/2023.03.08.531833

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Generation of a SARS-CoV-2 reverse genetics system and novel human lung cell lines that exhibit high virus-induced cytopathology

Juveriya Qamar Khan, Megha Rohamare, Karthic Rajamanickam, Kalpana K Bhanumathy, Jocelyne Lew, View ORCID ProfileAnil Kumar, View ORCID ProfileDarryl Falzarano, Franco J Vizeacoumar, View ORCID ProfileJoyce A Wilson

doi: https://doi.org/10.1101/2023.03.08.531833

Juveriya Qamar Khan

1Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada

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Megha Rohamare

1Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada

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Karthic Rajamanickam

2Division of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada

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Kalpana K Bhanumathy

2Division of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada

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Jocelyne Lew

3Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada

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Anil Kumar

1Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada

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ORCID record for Anil Kumar

Darryl Falzarano

3Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada

4Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK S7N 5B4 Canada

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ORCID record for Darryl Falzarano

Franco J Vizeacoumar

2Division of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada

5Cancer Research Department, Saskatchewan Cancer Agency, Saskatoon, SK S7N 5E5, Canada

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Joyce A Wilson

1Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada

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ORCID record for Joyce A Wilson
For correspondence: joyce.wilson@usask.ca

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Posted March 09, 2023.

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Generation of a SARS-CoV-2 reverse genetics system and novel human lung cell lines that exhibit high virus-induced cytopathology

Juveriya Qamar Khan, Megha Rohamare, Karthic Rajamanickam, Kalpana K Bhanumathy, Jocelyne Lew, Anil Kumar, Darryl Falzarano, Franco J Vizeacoumar, Joyce A Wilson

bioRxiv 2023.03.08.531833; doi: https://doi.org/10.1101/2023.03.08.531833

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Generation of a SARS-CoV-2 reverse genetics system and novel human lung cell lines that exhibit high virus-induced cytopathology

Juveriya Qamar Khan, Megha Rohamare, Karthic Rajamanickam, Kalpana K Bhanumathy, Jocelyne Lew, Anil Kumar, Darryl Falzarano, Franco J Vizeacoumar, Joyce A Wilson

bioRxiv 2023.03.08.531833; doi: https://doi.org/10.1101/2023.03.08.531833

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