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COMT inhibitor tolcapone represses the migration and invasion of trophoblast and results in preeclampsia-like phenotypes in mice

Lu Chen, Menglan Pang, Qiuling Jie, Fei Sun, Liping Huang, Yanlin Ma, Xiaojing Yue
doi: https://doi.org/10.1101/2023.03.17.530517
Lu Chen
1Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University
2Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong
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Menglan Pang
1Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University
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Qiuling Jie
3Hainan Provincial Key Laboratory for Human Reproductive Medicine and Genetic Research, The First Affiliated Hospital of Hainan Medical University, Hainan Medical University
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Fei Sun
1Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University
3Hainan Provincial Key Laboratory for Human Reproductive Medicine and Genetic Research, The First Affiliated Hospital of Hainan Medical University, Hainan Medical University
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Liping Huang
1Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University
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Yanlin Ma
3Hainan Provincial Key Laboratory for Human Reproductive Medicine and Genetic Research, The First Affiliated Hospital of Hainan Medical University, Hainan Medical University
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Xiaojing Yue
1Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University
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  • For correspondence: yuexj1986@163.com
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Article Information

doi 
https://doi.org/10.1101/2023.03.17.530517
History 
  • March 20, 2023.

Article Versions

  • You are currently viewing Version 1 of this article (March 20, 2023 - 16:12).
  • View Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Lu Chen1,2,
  2. Menglan Pang1,
  3. Qiuling Jie3,
  4. Fei Sun1,3,
  5. Liping Huang1,
  6. Yanlin Ma3 and
  7. Xiaojing Yue1,*
  1. 1Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University
  2. 2Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong
  3. 3Hainan Provincial Key Laboratory for Human Reproductive Medicine and Genetic Research, The First Affiliated Hospital of Hainan Medical University, Hainan Medical University
  1. ↵*Correspondence to:
    Xiaojing Yue, PhD (yuexj1986{at}163.com); Mailing address:
    Southern Medical University, 1023 South Shatai Rd, Guangzhou 510515, China.
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Posted March 20, 2023.
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COMT inhibitor tolcapone represses the migration and invasion of trophoblast and results in preeclampsia-like phenotypes in mice
Lu Chen, Menglan Pang, Qiuling Jie, Fei Sun, Liping Huang, Yanlin Ma, Xiaojing Yue
bioRxiv 2023.03.17.530517; doi: https://doi.org/10.1101/2023.03.17.530517
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COMT inhibitor tolcapone represses the migration and invasion of trophoblast and results in preeclampsia-like phenotypes in mice
Lu Chen, Menglan Pang, Qiuling Jie, Fei Sun, Liping Huang, Yanlin Ma, Xiaojing Yue
bioRxiv 2023.03.17.530517; doi: https://doi.org/10.1101/2023.03.17.530517

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