Click-to-Release: Cleavable Radioimmunoimaging with 89Zr-DFO-Trans-Cyclooctene-Trastuzumab Increases Tumor-to-Blood Ratio

Maria Vlastara; Raffaella Rossin; Freek J.M. Hoeben; Kim E. de Roode; Milou Boswinkel; Laurens H.J. Kleijn; James Nagarajah; Mark Rijpkema; Marc S. Robillard

doi:10.1101/2023.03.27.534155

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Click-to-Release: Cleavable Radioimmunoimaging with ⁸⁹Zr-DFO-Trans-Cyclooctene-Trastuzumab Increases Tumor-to-Blood Ratio

Maria Vlastara, Raffaella Rossin, Freek J.M. Hoeben, Kim E. de Roode, Milou Boswinkel, Laurens H.J. Kleijn, James Nagarajah, Mark Rijpkema, Marc S. Robillard

doi: https://doi.org/10.1101/2023.03.27.534155

Maria Vlastara

1Tagworks Pharmaceuticals, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands

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Raffaella Rossin

1Tagworks Pharmaceuticals, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands

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Freek J.M. Hoeben

2SyMO-Chem, Den Dolech 2, 5612 AZ Eindhoven, The Netherlands

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Kim E. de Roode

1Tagworks Pharmaceuticals, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands

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Milou Boswinkel

3Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands

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Laurens H.J. Kleijn

1Tagworks Pharmaceuticals, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands

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James Nagarajah

3Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands

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Mark Rijpkema

3Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA Nijmegen, The Netherlands

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Marc S. Robillard

1Tagworks Pharmaceuticals, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands

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For correspondence: marc.robillard@tagworkspharma.com

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Posted March 30, 2023.

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Click-to-Release: Cleavable Radioimmunoimaging with ⁸⁹Zr-DFO-Trans-Cyclooctene-Trastuzumab Increases Tumor-to-Blood Ratio

Maria Vlastara, Raffaella Rossin, Freek J.M. Hoeben, Kim E. de Roode, Milou Boswinkel, Laurens H.J. Kleijn, James Nagarajah, Mark Rijpkema, Marc S. Robillard

bioRxiv 2023.03.27.534155; doi: https://doi.org/10.1101/2023.03.27.534155

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Click-to-Release: Cleavable Radioimmunoimaging with ⁸⁹Zr-DFO-Trans-Cyclooctene-Trastuzumab Increases Tumor-to-Blood Ratio

Maria Vlastara, Raffaella Rossin, Freek J.M. Hoeben, Kim E. de Roode, Milou Boswinkel, Laurens H.J. Kleijn, James Nagarajah, Mark Rijpkema, Marc S. Robillard

bioRxiv 2023.03.27.534155; doi: https://doi.org/10.1101/2023.03.27.534155

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