Click chemistry selectively activates an auristatin protodrug with either intratumoral or systemic tumor-targeting agents

Jesse M. McFarland; Maša Alečković; George Coricor; Sangeetha Srinivasan; Matthew Tso; John Lee; Tri-Hung Nguyen; José M. Mejía Oneto

doi:10.1101/2023.03.28.534625

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Click chemistry selectively activates an auristatin protodrug with either intratumoral or systemic tumor-targeting agents

View ORCID ProfileJesse M. McFarland, View ORCID ProfileMaša Alečković, George Coricor, View ORCID ProfileSangeetha Srinivasan, Matthew Tso, John Lee, View ORCID ProfileTri-Hung Nguyen, View ORCID ProfileJosé M. Mejía Oneto

doi: https://doi.org/10.1101/2023.03.28.534625

Jesse M. McFarland

1Shasqi Inc., 665 3rd St, Suite 501, San Francisco, CA 94107, USA

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ORCID record for Jesse M. McFarland

Maša Alečković

1Shasqi Inc., 665 3rd St, Suite 501, San Francisco, CA 94107, USA

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George Coricor

1Shasqi Inc., 665 3rd St, Suite 501, San Francisco, CA 94107, USA

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Sangeetha Srinivasan

1Shasqi Inc., 665 3rd St, Suite 501, San Francisco, CA 94107, USA

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Matthew Tso

1Shasqi Inc., 665 3rd St, Suite 501, San Francisco, CA 94107, USA

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John Lee

1Shasqi Inc., 665 3rd St, Suite 501, San Francisco, CA 94107, USA

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Tri-Hung Nguyen

1Shasqi Inc., 665 3rd St, Suite 501, San Francisco, CA 94107, USA

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José M. Mejía Oneto

1Shasqi Inc., 665 3rd St, Suite 501, San Francisco, CA 94107, USA

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ORCID record for José M. Mejía Oneto
For correspondence: jose@shasqi.com

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Posted March 29, 2023.

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Click chemistry selectively activates an auristatin protodrug with either intratumoral or systemic tumor-targeting agents

Jesse M. McFarland, Maša Alečković, George Coricor, Sangeetha Srinivasan, Matthew Tso, John Lee, Tri-Hung Nguyen, José M. Mejía Oneto

bioRxiv 2023.03.28.534625; doi: https://doi.org/10.1101/2023.03.28.534625

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Click chemistry selectively activates an auristatin protodrug with either intratumoral or systemic tumor-targeting agents

Jesse M. McFarland, Maša Alečković, George Coricor, Sangeetha Srinivasan, Matthew Tso, John Lee, Tri-Hung Nguyen, José M. Mejía Oneto

bioRxiv 2023.03.28.534625; doi: https://doi.org/10.1101/2023.03.28.534625

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