A longitudinal resource for population neuroscience of school-age children and adolescents in China

ABSTRACT
During the past decade, cognitive neuroscience has been calling for population diversity to address the challenge of validity and generalizability, ushering in a new era of population neuroscience. The developing Chinese Color Nest Project (devCCNP, 2013-2022), a ten-year pilot stage of the lifespan CCNP (2013-2032), is an ongoing project focusing on brain-mind development. The project aims to create and share a large-scale, longitudinal and multimodal dataset of typically developing children and adolescents (ages 6.0–17.9 at enrolment) in the Chinese population. The devCCNP houses not only phenotypes measured by demographic, biophysical, psychological and behavioural, cognitive, affective, and ocular-tracking assessments but also neurotypes measured with magnetic resonance imaging (MRI) of brain morphometry, resting-state function, naturalistic viewing function and diffusion structure. This Data Descriptor introduces the first data release of devCCNP including a total of 864 visits from 479 participants. Herein, we provided details of the experimental design, sampling strategies, and technical validation of the devCCNP resource. We demonstrate and discuss the potential of a multicohort longitudinal design to depict normative brain growth curves from the perspective of developmental population neuroscience. The devCCNP resource is shared as part of the “Chinese Data-sharing Warehouse for In-vivo Imaging Brain” in the Chinese Color Nest Project (CCNP) – Lifespan Brain-Mind Development Data Community (https://www.scidb.cn/en/c/ccnp) at the Science Data Bank.
Design Types
Accelerated longitudinal design
Brain-mind development
Population imaging
Brain chart
Repeated measure
Measurements
Psychological behaviours
Biophysical and physical measures
Intelligence quotient measure
Neuroimaging
Sample Characteristic - Organism
Homo sapiens
Sample Characteristic - Environment
School- and community-based sample
Sample Characteristic - Location
Chongqing and Beijing, China
Duration
10 years (2013-2022)
Competing Interest Statement
The authors have declared no competing interest.
Footnotes
↵* LBCC is an international consortium and has aggregated 123,984 MRI scans, across more than 100 primary studies, from 101,457 human participants between 115 days post-conception to 100 years of age, and built brain charts to identify previously unreported neurodevelopmental milestones. More information are available at https://github.com/brainchart/lifespan.
↵** CCNP is a long-term effort (2013-2032) to build the lifespan brain-mind development cohort in China, and more consortium information are available at http://deepneuro.bnu.edu.cn/?p=163.
Subject Area
- Biochemistry (10810)
- Bioengineering (8053)
- Bioinformatics (27345)
- Biophysics (13998)
- Cancer Biology (11137)
- Cell Biology (16077)
- Clinical Trials (138)
- Developmental Biology (8793)
- Ecology (13307)
- Epidemiology (2067)
- Evolutionary Biology (17374)
- Genetics (11692)
- Genomics (15938)
- Immunology (11042)
- Microbiology (26129)
- Molecular Biology (10669)
- Neuroscience (56654)
- Paleontology (420)
- Pathology (1737)
- Pharmacology and Toxicology (3009)
- Physiology (4555)
- Plant Biology (9647)
- Synthetic Biology (2694)
- Systems Biology (6985)
- Zoology (1511)