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The anti-cancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3′ processing machinery
Liang Liu, Angela M Yu, Xiuye Wang, Lindsey V. Soles, Yiling Chen, Yoseop Yoon, Kristianna S.K. Sarkan, Marielle Cárdenas Valdez, Johannes Linder, Ivan Marazzi, Zhaoxia Yu, Feng Qiao, Wei Li, Georg Seelig, Yongsheng Shi
doi: https://doi.org/10.1101/2023.04.11.536453
Liang Liu
1Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
2Center for Virus Research, University of California, Irvine, Irvine, CA 92697, USA
9These authors contributed equally: Liang Liu, Angela M Yu Email: ;
Angela M Yu
3Department of Electrical and Computer Engineering, University of Washington, Seattle, Seattle, WA 98195, USA
9These authors contributed equally: Liang Liu, Angela M Yu Email: ;
Xiuye Wang
1Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
8Present address: Guangzhou Laboratory, Guangzhou, Guangdong, 510005, China
Lindsey V. Soles
1Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Yiling Chen
4Department of Biological Chemistry, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Yoseop Yoon
1Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Kristianna S.K. Sarkan
1Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Marielle Cárdenas Valdez
1Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Johannes Linder
5Department of Genetics, Stanford University, Stanford, CA 94305, USA
Ivan Marazzi
4Department of Biological Chemistry, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Zhaoxia Yu
6Department of Statistics, University of California, Irvine, Irvine, CA 92697, USA
Feng Qiao
4Department of Biological Chemistry, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Wei Li
4Department of Biological Chemistry, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Georg Seelig
3Department of Electrical and Computer Engineering, University of Washington, Seattle, Seattle, WA 98195, USA
7Paul G Allen School of Computer Science and Engineering, University of Washington, Seattle, Seattle, WA 98195, USA
Yongsheng Shi
1Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
2Center for Virus Research, University of California, Irvine, Irvine, CA 92697, USA
Article usage
Posted April 11, 2023.
The anti-cancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3′ processing machinery
Liang Liu, Angela M Yu, Xiuye Wang, Lindsey V. Soles, Yiling Chen, Yoseop Yoon, Kristianna S.K. Sarkan, Marielle Cárdenas Valdez, Johannes Linder, Ivan Marazzi, Zhaoxia Yu, Feng Qiao, Wei Li, Georg Seelig, Yongsheng Shi
bioRxiv 2023.04.11.536453; doi: https://doi.org/10.1101/2023.04.11.536453
The anti-cancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3′ processing machinery
Liang Liu, Angela M Yu, Xiuye Wang, Lindsey V. Soles, Yiling Chen, Yoseop Yoon, Kristianna S.K. Sarkan, Marielle Cárdenas Valdez, Johannes Linder, Ivan Marazzi, Zhaoxia Yu, Feng Qiao, Wei Li, Georg Seelig, Yongsheng Shi
bioRxiv 2023.04.11.536453; doi: https://doi.org/10.1101/2023.04.11.536453
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