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Open-loop lab-on-a-chip technology enables remote computer science training in Latinx life sciences students

Tyler Sano, View ORCID ProfileMohammad Julker Neyen Sampad, View ORCID ProfileJesus Gonzalez-Ferrer, Sebastian Hernandez, View ORCID ProfileSamira Vera-Choqqueccota, View ORCID ProfilePaola A. Vargas, View ORCID ProfileRoberto Urcuyo, View ORCID ProfileNatalia Montellano Duran, View ORCID ProfileMircea Teodorescu, View ORCID ProfileDavid Haussler, View ORCID ProfileHolger Schmidt, View ORCID ProfileMohammed A. Mostajo-Radji
doi: https://doi.org/10.1101/2023.04.28.538776
Tyler Sano
1Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064
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Mohammad Julker Neyen Sampad
1Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064
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  • ORCID record for Mohammad Julker Neyen Sampad
Jesus Gonzalez-Ferrer
2Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, 95060
3Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060
4Live Cell Biotechnology Discovery Lab, University of California Santa Cruz, Santa Cruz, CA, 95060
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Sebastian Hernandez
1Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064
3Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060
4Live Cell Biotechnology Discovery Lab, University of California Santa Cruz, Santa Cruz, CA, 95060
5Centro de Electroquímica y Energía Química (CELEQ), Universidad de Costa Rica, San José, 11501 2060, Costa Rica
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Samira Vera-Choqqueccota
2Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, 95060
3Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060
4Live Cell Biotechnology Discovery Lab, University of California Santa Cruz, Santa Cruz, CA, 95060
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Paola A. Vargas
6Biotechnology, Universidad Católica Boliviana San Pablo, Santa Cruz de la Sierra, Bolivia
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Roberto Urcuyo
5Centro de Electroquímica y Energía Química (CELEQ), Universidad de Costa Rica, San José, 11501 2060, Costa Rica
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Natalia Montellano Duran
6Biotechnology, Universidad Católica Boliviana San Pablo, Santa Cruz de la Sierra, Bolivia
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Mircea Teodorescu
1Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064
2Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, 95060
3Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060
4Live Cell Biotechnology Discovery Lab, University of California Santa Cruz, Santa Cruz, CA, 95060
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David Haussler
2Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, 95060
3Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060
4Live Cell Biotechnology Discovery Lab, University of California Santa Cruz, Santa Cruz, CA, 95060
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Holger Schmidt
1Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA, 95064
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  • For correspondence: hschmidt@ucsc.edu mmostajo@ucsc.edu
Mohammed A. Mostajo-Radji
3Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060
4Live Cell Biotechnology Discovery Lab, University of California Santa Cruz, Santa Cruz, CA, 95060
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  • For correspondence: hschmidt@ucsc.edu mmostajo@ucsc.edu
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ABSTRACT

Despite many interventions, science education remains highly inequitable throughout the world. Among all life sciences fields, Bioinformatics and Computational Biology suffer from the strongest underrepresentation of racial and gender minorities. Internet-enabled project-based learning (PBL) has the potential to reach underserved communities and increase the diversity of the scientific workforce. Here, we demonstrate the use of lab-on-a-chip (LoC) technologies to train Latinx life science undergraduate students in concepts of computer programming by taking advantage of open-loop cloud-integrated LoCs. We developed a context-aware curriculum to train students at over 8,000 km from the experimental site. We showed that this approach was sufficient to develop programming skills and increase the interest of students in continuing careers in Bioinformatics. Altogether, we conclude that LoC-based Internet-enabled PBL can become a powerful tool to train Latinx students and increase the diversity in STEM.

Competing Interest Statement

M.A.M.-R. is a cofounder of Paika, a company for remote people-to-people interactions. H.S. had a financial interest in Fluxus Inc., which commercializes optofluidic technology. The authors declare no other conflicts of interests.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted May 01, 2023.
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Open-loop lab-on-a-chip technology enables remote computer science training in Latinx life sciences students
Tyler Sano, Mohammad Julker Neyen Sampad, Jesus Gonzalez-Ferrer, Sebastian Hernandez, Samira Vera-Choqqueccota, Paola A. Vargas, Roberto Urcuyo, Natalia Montellano Duran, Mircea Teodorescu, David Haussler, Holger Schmidt, Mohammed A. Mostajo-Radji
bioRxiv 2023.04.28.538776; doi: https://doi.org/10.1101/2023.04.28.538776
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Open-loop lab-on-a-chip technology enables remote computer science training in Latinx life sciences students
Tyler Sano, Mohammad Julker Neyen Sampad, Jesus Gonzalez-Ferrer, Sebastian Hernandez, Samira Vera-Choqqueccota, Paola A. Vargas, Roberto Urcuyo, Natalia Montellano Duran, Mircea Teodorescu, David Haussler, Holger Schmidt, Mohammed A. Mostajo-Radji
bioRxiv 2023.04.28.538776; doi: https://doi.org/10.1101/2023.04.28.538776

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