Stability Oracle: A Structure-Based Graph-Transformer for Identifying Stabilizing Mutations

Daniel J. Diaz; Chengyue Gong; Jeffrey Ouyang-Zhang; James M. Loy; Jordan Wells; David Yang; Andrew D. Ellington; Alex Dimakis; Adam R. Klivans

doi:10.1101/2023.05.15.540857

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Stability Oracle: A Structure-Based Graph-Transformer for Identifying Stabilizing Mutations

View ORCID ProfileDaniel J. Diaz, View ORCID ProfileChengyue Gong, Jeffrey Ouyang-Zhang, View ORCID ProfileJames M. Loy, Jordan Wells, David Yang, View ORCID ProfileAndrew D. Ellington, Alex Dimakis, Adam R. Klivans

doi: https://doi.org/10.1101/2023.05.15.540857

Daniel J. Diaz

1Department of Computer Science, UT Austin

2Intelligent Proteins, LLC

3Department of Chemistry, UT Austin

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For correspondence: danny.diaz@utexas.edu

Chengyue Gong

1Department of Computer Science, UT Austin

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Jeffrey Ouyang-Zhang

1Department of Computer Science, UT Austin

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James M. Loy

2Intelligent Proteins, LLC

5Department of Molecular Biosciences, UT Austin

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Jordan Wells

4McKetta Department of Chemical Engineering, UT Austin

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David Yang

5Department of Molecular Biosciences, UT Austin

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Andrew D. Ellington

5Department of Molecular Biosciences, UT Austin

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Alex Dimakis

6Chandra Family Department of Electrical and Computer Engineering, UT Austin

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Adam R. Klivans

1Department of Computer Science, UT Austin

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Stability Oracle: A Structure-Based Graph-Transformer for Identifying Stabilizing Mutations

Daniel J. Diaz, Chengyue Gong, Jeffrey Ouyang-Zhang, James M. Loy, Jordan Wells, David Yang, Andrew D. Ellington, Alex Dimakis, Adam R. Klivans

bioRxiv 2023.05.15.540857; doi: https://doi.org/10.1101/2023.05.15.540857

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Stability Oracle: A Structure-Based Graph-Transformer for Identifying Stabilizing Mutations

Daniel J. Diaz, Chengyue Gong, Jeffrey Ouyang-Zhang, James M. Loy, Jordan Wells, David Yang, Andrew D. Ellington, Alex Dimakis, Adam R. Klivans

bioRxiv 2023.05.15.540857; doi: https://doi.org/10.1101/2023.05.15.540857

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