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Pathformer: biological pathway informed Transformer model integrating multi-modal data of cancer
Xiaofan Liu, Yuhuan Tao, Zilin Cai, Pengfei Bao, Hongli Ma, Kexing Li, Yunping Zhu, View ORCID ProfileZhi John Lu
doi: https://doi.org/10.1101/2023.05.23.541554
Xiaofan Liu
1MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China
2Institute for Precision Medicine, Tsinghua University, Beijing 100084, China
Yuhuan Tao
1MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China
2Institute for Precision Medicine, Tsinghua University, Beijing 100084, China
Zilin Cai
1MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China
Pengfei Bao
1MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China
2Institute for Precision Medicine, Tsinghua University, Beijing 100084, China
Hongli Ma
1MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China
2Institute for Precision Medicine, Tsinghua University, Beijing 100084, China
Kexing Li
1MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China
Yunping Zhu
3State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, 38 Life Science Park, Changping District, Beijing 102206, China
Zhi John Lu
1MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China
2Institute for Precision Medicine, Tsinghua University, Beijing 100084, China
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Posted May 24, 2023.
Pathformer: biological pathway informed Transformer model integrating multi-modal data of cancer
Xiaofan Liu, Yuhuan Tao, Zilin Cai, Pengfei Bao, Hongli Ma, Kexing Li, Yunping Zhu, Zhi John Lu
bioRxiv 2023.05.23.541554; doi: https://doi.org/10.1101/2023.05.23.541554
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