A synthetic human bone marrow extracellular matrix identifies tunnelling nanotubules as druggable mediators of functional cancer-niche crosstalk

Sean Hockney; Jess Parker; Babis Tzivelekis; Blair Helen; Kenny Dalgarno; Deepali Pal

doi:10.1101/2023.06.20.545732

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A synthetic human bone marrow extracellular matrix identifies tunnelling nanotubules as druggable mediators of functional cancer-niche crosstalk

Sean Hockney, Jess Parker, Babis Tzivelekis, Blair Helen, Kenny Dalgarno, Deepali Pal

doi: https://doi.org/10.1101/2023.06.20.545732

Sean Hockney

2Department of Applied Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST. UK

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Jess Parker

2Department of Applied Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST. UK

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Babis Tzivelekis

4School of Engineering, M18A, Stephenson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU

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Blair Helen

3Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Herschel Building Level 6, Brewery Lane, Newcastle upon Tyne, NE1 7RU. UK

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Kenny Dalgarno

4School of Engineering, M18A, Stephenson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU

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Deepali Pal

1School of Cellular and Molecular Medicine, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD

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For correspondence: deepali.pal@bristol.ac.uk

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A synthetic human bone marrow extracellular matrix identifies tunnelling nanotubules as druggable mediators of functional cancer-niche crosstalk

Sean Hockney, Jess Parker, Babis Tzivelekis, Blair Helen, Kenny Dalgarno, Deepali Pal

bioRxiv 2023.06.20.545732; doi: https://doi.org/10.1101/2023.06.20.545732

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A synthetic human bone marrow extracellular matrix identifies tunnelling nanotubules as druggable mediators of functional cancer-niche crosstalk

Sean Hockney, Jess Parker, Babis Tzivelekis, Blair Helen, Kenny Dalgarno, Deepali Pal

bioRxiv 2023.06.20.545732; doi: https://doi.org/10.1101/2023.06.20.545732

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